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Jun 11

Human-Centric Video Anomaly Detection Through Spatio-Temporal Pose Tokenization and Transformer

Video Anomaly Detection (VAD) presents a significant challenge in computer vision, particularly due to the unpredictable and infrequent nature of anomalous events, coupled with the diverse and dynamic environments in which they occur. Human-centric VAD, a specialized area within this domain, faces additional complexities, including variations in human behavior, potential biases in data, and substantial privacy concerns related to human subjects. These issues complicate the development of models that are both robust and generalizable. To address these challenges, recent advancements have focused on pose-based VAD, which leverages human pose as a high-level feature to mitigate privacy concerns, reduce appearance biases, and minimize background interference. In this paper, we introduce SPARTA, a novel transformer-based architecture designed specifically for human-centric pose-based VAD. SPARTA introduces an innovative Spatio-Temporal Pose and Relative Pose (ST-PRP) tokenization method that produces an enriched representation of human motion over time. This approach ensures that the transformer's attention mechanism captures both spatial and temporal patterns simultaneously, rather than focusing on only one aspect. The addition of the relative pose further emphasizes subtle deviations from normal human movements. The architecture's core, a novel Unified Encoder Twin Decoders (UETD) transformer, significantly improves the detection of anomalous behaviors in video data. Extensive evaluations across multiple benchmark datasets demonstrate that SPARTA consistently outperforms existing methods, establishing a new state-of-the-art in pose-based VAD.

  • 3 authors
·
Aug 27, 2024

Learning Physiology-Informed Vocal Spectrotemporal Representations for Speech Emotion Recognition

Speech emotion recognition (SER) is essential for humanoid robot tasks such as social robotic interactions and robotic psychological diagnosis, where interpretable and efficient models are critical for safety and performance. Existing deep models trained on large datasets remain largely uninterpretable, often insufficiently modeling underlying emotional acoustic signals and failing to capture and analyze the core physiology of emotional vocal behaviors. Physiological research on human voices shows that the dynamics of vocal amplitude and phase correlate with emotions through the vocal tract filter and the glottal source. However, most existing deep models solely involve amplitude but fail to couple the physiological features of and between amplitude and phase. Here, we propose PhysioSER, a physiology-informed vocal spectrotemporal representation learning method, to address these issues with a compact, plug-and-play design. PhysioSER constructs amplitude and phase views informed by voice anatomy and physiology (VAP) to complement SSL models for SER. This VAP-informed framework incorporates two parallel workflows: a vocal feature representation branch to decompose vocal signals based on VAP, embed them into a quaternion field, and use Hamilton-structured quaternion convolutions for modeling their dynamic interactions; and a latent representation branch based on a frozen SSL backbone. Then, utterance-level features from both workflows are aligned by a Contrastive Projection and Alignment framework, followed by a shallow attention fusion head for SER classification. PhysioSER is shown to be interpretable and efficient for SER through extensive evaluations across 14 datasets, 10 languages, and 6 backbones, and its practical efficacy is validated by real-time deployment on a humanoid robotic platform.

  • 4 authors
·
Feb 2

HuMo: Human-Centric Video Generation via Collaborative Multi-Modal Conditioning

Human-Centric Video Generation (HCVG) methods seek to synthesize human videos from multimodal inputs, including text, image, and audio. Existing methods struggle to effectively coordinate these heterogeneous modalities due to two challenges: the scarcity of training data with paired triplet conditions and the difficulty of collaborating the sub-tasks of subject preservation and audio-visual sync with multimodal inputs. In this work, we present HuMo, a unified HCVG framework for collaborative multimodal control. For the first challenge, we construct a high-quality dataset with diverse and paired text, reference images, and audio. For the second challenge, we propose a two-stage progressive multimodal training paradigm with task-specific strategies. For the subject preservation task, to maintain the prompt following and visual generation abilities of the foundation model, we adopt the minimal-invasive image injection strategy. For the audio-visual sync task, besides the commonly adopted audio cross-attention layer, we propose a focus-by-predicting strategy that implicitly guides the model to associate audio with facial regions. For joint learning of controllabilities across multimodal inputs, building on previously acquired capabilities, we progressively incorporate the audio-visual sync task. During inference, for flexible and fine-grained multimodal control, we design a time-adaptive Classifier-Free Guidance strategy that dynamically adjusts guidance weights across denoising steps. Extensive experimental results demonstrate that HuMo surpasses specialized state-of-the-art methods in sub-tasks, establishing a unified framework for collaborative multimodal-conditioned HCVG. Project Page: https://phantom-video.github.io/HuMo.

  • 10 authors
·
Sep 10, 2025 5

LibriVAD: A Scalable Open Dataset with Deep Learning Benchmarks for Voice Activity Detection

Robust Voice Activity Detection (VAD) remains a challenging task, especially under noisy, diverse, and unseen acoustic conditions. Beyond algorithmic development, a key limitation in advancing VAD research is the lack of large-scale, systematically controlled, and publicly available datasets. To address this, we introduce LibriVAD - a scalable open-source dataset derived from LibriSpeech and augmented with diverse real-world and synthetic noise sources. LibriVAD enables systematic control over speech-to-noise ratio, silence-to-speech ratio (SSR), and noise diversity, and is released in three sizes (15 GB, 150 GB, and 1.5 TB) with two variants (LibriVAD-NonConcat and LibriVAD-Concat) to support different experimental setups. We benchmark multiple feature-model combinations, including waveform, Mel-Frequency Cepstral Coefficients (MFCC), and Gammatone filter bank cepstral coefficients, and introduce the Vision Transformer (ViT) architecture for VAD. Our experiments show that ViT with MFCC features consistently outperforms established VAD models such as boosted deep neural network and convolutional long short-term memory deep neural network across seen, unseen, and out-of-distribution (OOD) conditions, including evaluation on the real-world VOiCES dataset. We further analyze the impact of dataset size and SSR on model generalization, experimentally showing that scaling up dataset size and balancing SSR noticeably and consistently enhance VAD performance under OOD conditions. All datasets, trained models, and code are publicly released to foster reproducibility and accelerate progress in VAD research.

  • 5 authors
·
Dec 19, 2025

OpenHumanVid: A Large-Scale High-Quality Dataset for Enhancing Human-Centric Video Generation

Recent advancements in visual generation technologies have markedly increased the scale and availability of video datasets, which are crucial for training effective video generation models. However, a significant lack of high-quality, human-centric video datasets presents a challenge to progress in this field. To bridge this gap, we introduce OpenHumanVid, a large-scale and high-quality human-centric video dataset characterized by precise and detailed captions that encompass both human appearance and motion states, along with supplementary human motion conditions, including skeleton sequences and speech audio. To validate the efficacy of this dataset and the associated training strategies, we propose an extension of existing classical diffusion transformer architectures and conduct further pretraining of our models on the proposed dataset. Our findings yield two critical insights: First, the incorporation of a large-scale, high-quality dataset substantially enhances evaluation metrics for generated human videos while preserving performance in general video generation tasks. Second, the effective alignment of text with human appearance, human motion, and facial motion is essential for producing high-quality video outputs. Based on these insights and corresponding methodologies, the straightforward extended network trained on the proposed dataset demonstrates an obvious improvement in the generation of human-centric videos. Project page https://fudan-generative-vision.github.io/OpenHumanVid

  • 11 authors
·
Nov 28, 2024

Explainable Multi-Modal Deep Learning for Automatic Detection of Lung Diseases from Respiratory Audio Signals

Respiratory diseases remain major global health challenges, and traditional auscultation is often limited by subjectivity, environmental noise, and inter-clinician variability. This study presents an explainable multimodal deep learning framework for automatic lung-disease detection using respiratory audio signals. The proposed system integrates two complementary representations: a spectral-temporal encoder based on a CNN-BiLSTM Attention architecture, and a handcrafted acoustic-feature encoder capturing physiologically meaningful descriptors such as MFCCs, spectral centroid, spectral bandwidth, and zero-crossing rate. These branches are combined through late-stage fusion to leverage both data-driven learning and domain-informed acoustic cues. The model is trained and evaluated on the Asthma Detection Dataset Version 2 using rigorous preprocessing, including resampling, normalization, noise filtering, data augmentation, and patient-level stratified partitioning. The study achieved strong generalization with 91.21% accuracy, 0.899 macro F1-score, and 0.9866 macro ROC-AUC, outperforming all ablated variants. An ablation study confirms the importance of temporal modeling, attention mechanisms, and multimodal fusion. The framework incorporates Grad-CAM, Integrated Gradients, and SHAP, generating interpretable spectral, temporal, and feature-level explanations aligned with known acoustic biomarkers to build clinical transparency. The findings demonstrate the framework's potential for telemedicine, point-of-care diagnostics, and real-world respiratory screening.

  • 4 authors
·
Nov 29, 2025

FireRedChat: A Pluggable, Full-Duplex Voice Interaction System with Cascaded and Semi-Cascaded Implementations

Full-duplex voice interaction allows users and agents to speak simultaneously with controllable barge-in, enabling lifelike assistants and customer service. Existing solutions are either end-to-end, difficult to design and hard to control, or modular pipelines governed by turn-taking controllers that ease upgrades and per-module optimization; however, prior modular frameworks depend on non-open components and external providers, limiting holistic optimization. In this work, we present a complete, practical full-duplex voice interaction system comprising a turn-taking controller, an interaction module, and a dialogue manager. The controller integrates streaming personalized VAD (pVAD) to suppress false barge-ins from noise and non-primary speakers, precisely timestamp primary-speaker segments, and explicitly enable primary-speaker barge-ins; a semantic end-of-turn detector improves stop decisions. It upgrades heterogeneous half-duplex pipelines, cascaded, semi-cascaded, and speech-to-speech, to full duplex. Using internal models, we implement cascaded and semi-cascaded variants; the semi-cascaded one captures emotional and paralinguistic cues, yields more coherent responses, lowers latency and error propagation, and improves robustness. A dialogue manager extends capabilities via tool invocation and context management. We also propose three system-level metrics, barge-in, end-of-turn detection accuracy, and end-to-end latency, to assess naturalness, control accuracy, and efficiency. Experiments show fewer false interruptions, more accurate semantic ends, and lower latency approaching industrial systems, enabling robust, natural, real-time full-duplex interaction. Demos: https://fireredteam.github.io/demos/firered_chat.

  • 15 authors
·
Sep 8, 2025

VAD: Vectorized Scene Representation for Efficient Autonomous Driving

Autonomous driving requires a comprehensive understanding of the surrounding environment for reliable trajectory planning. Previous works rely on dense rasterized scene representation (e.g., agent occupancy and semantic map) to perform planning, which is computationally intensive and misses the instance-level structure information. In this paper, we propose VAD, an end-to-end vectorized paradigm for autonomous driving, which models the driving scene as a fully vectorized representation. The proposed vectorized paradigm has two significant advantages. On one hand, VAD exploits the vectorized agent motion and map elements as explicit instance-level planning constraints which effectively improves planning safety. On the other hand, VAD runs much faster than previous end-to-end planning methods by getting rid of computation-intensive rasterized representation and hand-designed post-processing steps. VAD achieves state-of-the-art end-to-end planning performance on the nuScenes dataset, outperforming the previous best method by a large margin. Our base model, VAD-Base, greatly reduces the average collision rate by 29.0% and runs 2.5x faster. Besides, a lightweight variant, VAD-Tiny, greatly improves the inference speed (up to 9.3x) while achieving comparable planning performance. We believe the excellent performance and the high efficiency of VAD are critical for the real-world deployment of an autonomous driving system. Code and models are available at https://github.com/hustvl/VAD for facilitating future research.

  • 10 authors
·
Mar 21, 2023

HyCoVAD: A Hybrid SSL-LLM Model for Complex Video Anomaly Detection

Video anomaly detection (VAD) is crucial for intelligent surveillance, but a significant challenge lies in identifying complex anomalies, which are events defined by intricate relationships and temporal dependencies among multiple entities rather than by isolated actions. While self-supervised learning (SSL) methods effectively model low-level spatiotemporal patterns, they often struggle to grasp the semantic meaning of these interactions. Conversely, large language models (LLMs) offer powerful contextual reasoning but are computationally expensive for frame-by-frame analysis and lack fine-grained spatial localization. We introduce HyCoVAD, Hybrid Complex Video Anomaly Detection, a hybrid SSL-LLM model that combines a multi-task SSL temporal analyzer with LLM validator. The SSL module is built upon an nnFormer backbone which is a transformer-based model for image segmentation. It is trained with multiple proxy tasks, learns from video frames to identify those suspected of anomaly. The selected frames are then forwarded to the LLM, which enriches the analysis with semantic context by applying structured, rule-based reasoning to validate the presence of anomalies. Experiments on the challenging ComplexVAD dataset show that HyCoVAD achieves a 72.5% frame-level AUC, outperforming existing baselines by 12.5% while reducing LLM computation. We release our interaction anomaly taxonomy, adaptive thresholding protocol, and code to facilitate future research in complex VAD scenarios.

  • 7 authors
·
Sep 26, 2025

Cough-E: A multimodal, privacy-preserving cough detection algorithm for the edge

Continuous cough monitors can greatly aid doctors in home monitoring and treatment of respiratory diseases. Although many algorithms have been proposed, they still face limitations in data privacy and short-term monitoring. Edge-AI offers a promising solution by processing privacy-sensitive data near the source, but challenges arise in deploying resource-intensive algorithms on constrained devices. From a suitable selection of audio and kinematic signals, our methodology aims at the optimal selection of features via Recursive Feature Elimination with Cross-Validation (RFECV), which exploits the explainability of the selected XGB model. Additionally, it analyzes the use of Mel spectrogram features, instead of the more common MFCC. Moreover, a set of hyperparameters for a multimodal implementation of the classifier is explored. Finally, it evaluates the performance based on clinically relevant event-based metrics. We apply our methodology to develop Cough-E, an energy-efficient, multimodal and edge AI cough detection algorithm. It exploits audio and kinematic data in two distinct classifiers, jointly cooperating for a balanced energy and performance trade-off. We demonstrate that our algorithm can be executed in real-time on an ARM Cortex M33 microcontroller. Cough-E achieves a 70.56\% energy saving when compared to the audio-only approach, at the cost of a 1.26\% relative performance drop, resulting in a 0.78 F1-score. Both Cough-E and the edge-aware model optimization methodology are publicly available as open-source code. This approach demonstrates the benefits of the proposed hardware-aware methodology to enable privacy-preserving cough monitors on the edge, paving the way to efficient cough monitoring.

  • 7 authors
·
Oct 31, 2024

Towards Open Respiratory Acoustic Foundation Models: Pretraining and Benchmarking

Respiratory audio, such as coughing and breathing sounds, has predictive power for a wide range of healthcare applications, yet is currently under-explored. The main problem for those applications arises from the difficulty in collecting large labeled task-specific data for model development. Generalizable respiratory acoustic foundation models pretrained with unlabeled data would offer appealing advantages and possibly unlock this impasse. However, given the safety-critical nature of healthcare applications, it is pivotal to also ensure openness and replicability for any proposed foundation model solution. To this end, we introduce OPERA, an OPEn Respiratory Acoustic foundation model pretraining and benchmarking system, as the first approach answering this need. We curate large-scale respiratory audio datasets (~136K samples, 440 hours), pretrain three pioneering foundation models, and build a benchmark consisting of 19 downstream respiratory health tasks for evaluation. Our pretrained models demonstrate superior performance (against existing acoustic models pretrained with general audio on 16 out of 19 tasks) and generalizability (to unseen datasets and new respiratory audio modalities). This highlights the great promise of respiratory acoustic foundation models and encourages more studies using OPERA as an open resource to accelerate research on respiratory audio for health. The system is accessible from https://github.com/evelyn0414/OPERA.

  • 9 authors
·
Jun 23, 2024

Reliable Physiological Monitoring on the Wrist Using Generative Deep Learning to Address Poor Skin-Sensor Contact

Photoplethysmography (PPG) is a widely adopted, non-invasive technique for monitoring cardiovascular health and physiological parameters in both consumer and clinical settings. While motion artifacts in dynamic environments have been extensively studied, suboptimal skin-sensor contact in sedentary conditions - a critical yet underexplored issue - can distort PPG waveform morphology, leading to the loss or misalignment of key features and compromising sensing accuracy. In this work, we propose CP-PPG, a novel framework that transforms Contact Pressure-distorted PPG signals into high-fidelity waveforms with ideal morphology. CP-PPG integrates a custom data collection protocol, a carefully designed signal processing pipeline, and a novel deep adversarial model trained with a custom PPG-aware loss function. We validated CP-PPG through comprehensive evaluations, including 1) morphology transformation performance on our self-collected dataset, 2) downstream physiological monitoring performance on public datasets, and 3) in-the-wild study. Extensive experiments demonstrate substantial and consistent improvements in signal fidelity (Mean Absolute Error: 0.09, 40% improvement over the original signal) as well as downstream performance across all evaluations in Heart Rate (HR), Heart Rate Variability (HRV), Respiration Rate (RR), and Blood Pressure (BP) estimation (on average, 21% improvement in HR; 41-46% in HRV; 6% in RR; and 4-5% in BP). These findings highlight the critical importance of addressing skin-sensor contact issues to enhance the reliability and effectiveness of PPG-based physiological monitoring. CP-PPG thus holds significant potential to improve the accuracy of wearable health technologies in clinical and consumer applications.

  • 6 authors
·
Apr 15, 2025

MARCUS: An agentic, multimodal vision-language model for cardiac diagnosis and management

Cardiovascular disease remains the leading cause of global mortality, with progress hindered by human interpretation of complex cardiac tests. Current AI vision-language models are limited to single-modality inputs and are non-interactive. We present MARCUS (Multimodal Autonomous Reasoning and Chat for Ultrasound and Signals), an agentic vision-language system for end-to-end interpretation of electrocardiograms (ECGs), echocardiograms, and cardiac magnetic resonance imaging (CMR) independently and as multimodal input. MARCUS employs a hierarchical agentic architecture comprising modality-specific vision-language expert models, each integrating domain-trained visual encoders with multi-stage language model optimization, coordinated by a multimodal orchestrator. Trained on 13.5 million images (0.25M ECGs, 1.3M echocardiogram images, 12M CMR images) and our novel expert-curated dataset spanning 1.6 million questions, MARCUS achieves state-of-the-art performance surpassing frontier models (GPT-5 Thinking, Gemini 2.5 Pro Deep Think). Across internal (Stanford) and external (UCSF) test cohorts, MARCUS achieves accuracies of 87-91% for ECG, 67-86% for echocardiography, and 85-88% for CMR, outperforming frontier models by 34-45% (P<0.001). On multimodal cases, MARCUS achieved 70% accuracy, nearly triple that of frontier models (22-28%), with 1.7-3.0x higher free-text quality scores. Our agentic architecture also confers resistance to mirage reasoning, whereby vision-language models derive reasoning from unintended textual signals or hallucinated visual content. MARCUS demonstrates that domain-specific visual encoders with an agentic orchestrator enable multimodal cardiac interpretation. We release our models, code, and benchmark open-source.

  • 11 authors
·
Mar 23

DNA-Rendering: A Diverse Neural Actor Repository for High-Fidelity Human-centric Rendering

Realistic human-centric rendering plays a key role in both computer vision and computer graphics. Rapid progress has been made in the algorithm aspect over the years, yet existing human-centric rendering datasets and benchmarks are rather impoverished in terms of diversity, which are crucial for rendering effect. Researchers are usually constrained to explore and evaluate a small set of rendering problems on current datasets, while real-world applications require methods to be robust across different scenarios. In this work, we present DNA-Rendering, a large-scale, high-fidelity repository of human performance data for neural actor rendering. DNA-Rendering presents several alluring attributes. First, our dataset contains over 1500 human subjects, 5000 motion sequences, and 67.5M frames' data volume. Second, we provide rich assets for each subject -- 2D/3D human body keypoints, foreground masks, SMPLX models, cloth/accessory materials, multi-view images, and videos. These assets boost the current method's accuracy on downstream rendering tasks. Third, we construct a professional multi-view system to capture data, which contains 60 synchronous cameras with max 4096 x 3000 resolution, 15 fps speed, and stern camera calibration steps, ensuring high-quality resources for task training and evaluation. Along with the dataset, we provide a large-scale and quantitative benchmark in full-scale, with multiple tasks to evaluate the existing progress of novel view synthesis, novel pose animation synthesis, and novel identity rendering methods. In this manuscript, we describe our DNA-Rendering effort as a revealing of new observations, challenges, and future directions to human-centric rendering. The dataset, code, and benchmarks will be publicly available at https://dna-rendering.github.io/

  • 21 authors
·
Jul 19, 2023

Artificial Intelligence-derived Vascular Age from Photoplethysmography: A Novel Digital Biomarker for Cardiovascular Health

With the increasing availability of wearable devices, photoplethysmography (PPG) has emerged as a promising non-invasive tool for monitoring human hemodynamics. We propose a deep learning framework to estimate vascular age (AI-vascular age) from PPG signals, incorporating a distribution-aware loss to address biases caused by imbalanced data. The model was developed using data from the UK Biobank (UKB), with 98,672 participants in the development cohort and 113,559 participants (144,683 data pairs) for clinical evaluation. After adjusting for key confounders, individuals with a vascular age gap (AI-vascular age minus calendar age) exceeding 9 years had a significantly higher risk of major adverse cardiovascular and cerebrovascular events (MACCE) (HR = 2.37, p < 0.005) and secondary outcomes, including diabetes (HR = 2.69, p < 0.005), hypertension (HR = 2.88, p < 0.005), coronary heart disease (HR = 2.20, p < 0.005), heart failure (HR = 2.15, p < 0.005), myocardial infarction (HR = 2.51, p < 0.005), stroke (HR = 2.55, p < 0.005), and all-cause mortality (HR = 2.51, p < 0.005). Conversely, participants with a vascular age gap below -9 years exhibited a significantly lower incidence of these outcomes. We further evaluated the longitudinal applicability of AI-vascular age using serial PPG data from the UKB, demonstrating its value in risk stratification by leveraging AI-vascular age at two distinct time points to predict future MACCE incidence. External validation was performed on a MIMIC-III-derived cohort (n = 2,343), where each one-year increase in vascular age gap was significantly associated with elevated in-hospital mortality risk (OR = 1.02, p < 0.005). In conclusion, our study establishes AI-vascular age as a novel, non-invasive digital biomarker for cardiovascular health assessment.

  • 5 authors
·
Feb 18, 2025

Next-Token Prediction Learns Generalisable Representations of Sleep Physiology

Foundation models offer a promising route to compress multi-modal physiological signals into compact representations of human health, with broad applications across sleep medicine, cardiology, neurology and other healthcare domains. Existing models have typically been trained with masked-reconstruction or contrastive objectives. However, masked reconstruction may be poorly suited to the stochastic nature of these signals, while contrastive approaches rely on positive-pair definitions despite the semantic invariances of physiological signals being poorly understood. In this work, we show that next-token prediction is a simple and scalable alternative. We develop Hypnos, a multi-modal sleep foundation model trained using eight different sensing modalities (e.g. EEG, ECG, respiratory signals) drawn from over 20,000 overnight polysomnography recordings. We tokenize each modality into streams of discrete tokens using residual vector quantization, then train a large auto-regressive RQ-Transformer to jointly predict the next token across all modalities in parallel. After training, Hypnos can be applied to continuous streams of sensor data from any subset of supported modalities, generating embeddings for downstream tasks. Across a range of benchmarks, Hypnos significantly outperforms existing foundation models. In sleep stage classification, we match the performance of strong supervised baselines on held-out test sets whilst using \(100\times\) less labelled data. Hypnos even generalises to daytime physiology, surpassing a dedicated ECG foundation model at detecting atrial fibrillation. Our results demonstrate that next-token prediction is a strong self-supervised objective for representation learning from multi-modal physiological signals.

  • 2 authors
·
Jun 7

HyperHuman: Hyper-Realistic Human Generation with Latent Structural Diffusion

Despite significant advances in large-scale text-to-image models, achieving hyper-realistic human image generation remains a desirable yet unsolved task. Existing models like Stable Diffusion and DALL-E 2 tend to generate human images with incoherent parts or unnatural poses. To tackle these challenges, our key insight is that human image is inherently structural over multiple granularities, from the coarse-level body skeleton to fine-grained spatial geometry. Therefore, capturing such correlations between the explicit appearance and latent structure in one model is essential to generate coherent and natural human images. To this end, we propose a unified framework, HyperHuman, that generates in-the-wild human images of high realism and diverse layouts. Specifically, 1) we first build a large-scale human-centric dataset, named HumanVerse, which consists of 340M images with comprehensive annotations like human pose, depth, and surface normal. 2) Next, we propose a Latent Structural Diffusion Model that simultaneously denoises the depth and surface normal along with the synthesized RGB image. Our model enforces the joint learning of image appearance, spatial relationship, and geometry in a unified network, where each branch in the model complements to each other with both structural awareness and textural richness. 3) Finally, to further boost the visual quality, we propose a Structure-Guided Refiner to compose the predicted conditions for more detailed generation of higher resolution. Extensive experiments demonstrate that our framework yields the state-of-the-art performance, generating hyper-realistic human images under diverse scenarios. Project Page: https://snap-research.github.io/HyperHuman/

  • 9 authors
·
Oct 12, 2023 1

RefHCM: A Unified Model for Referring Perceptions in Human-Centric Scenarios

Human-centric perceptions play a crucial role in real-world applications. While recent human-centric works have achieved impressive progress, these efforts are often constrained to the visual domain and lack interaction with human instructions, limiting their applicability in broader scenarios such as chatbots and sports analysis. This paper introduces Referring Human Perceptions, where a referring prompt specifies the person of interest in an image. To tackle the new task, we propose RefHCM (Referring Human-Centric Model), a unified framework to integrate a wide range of human-centric referring tasks. Specifically, RefHCM employs sequence mergers to convert raw multimodal data -- including images, text, coordinates, and parsing maps -- into semantic tokens. This standardized representation enables RefHCM to reformulate diverse human-centric referring tasks into a sequence-to-sequence paradigm, solved using a plain encoder-decoder transformer architecture. Benefiting from a unified learning strategy, RefHCM effectively facilitates knowledge transfer across tasks and exhibits unforeseen capabilities in handling complex reasoning. This work represents the first attempt to address referring human perceptions with a general-purpose framework, while simultaneously establishing a corresponding benchmark that sets new standards for the field. Extensive experiments showcase RefHCM's competitive and even superior performance across multiple human-centric referring tasks. The code and data are publicly at https://github.com/JJJYmmm/RefHCM.

  • 5 authors
·
Dec 19, 2024

X-Fi: A Modality-Invariant Foundation Model for Multimodal Human Sensing

Human sensing, which employs various sensors and advanced deep learning technologies to accurately capture and interpret human body information, has significantly impacted fields like public security and robotics. However, current human sensing primarily depends on modalities such as cameras and LiDAR, each of which has its own strengths and limitations. Furthermore, existing multi-modal fusion solutions are typically designed for fixed modality combinations, requiring extensive retraining when modalities are added or removed for diverse scenarios. In this paper, we propose a modality-invariant foundation model for all modalities, X-Fi, to address this issue. X-Fi enables the independent or combinatory use of sensor modalities without additional training by utilizing a transformer structure to accommodate variable input sizes and incorporating a novel "X-fusion" mechanism to preserve modality-specific features during multimodal integration. This approach not only enhances adaptability but also facilitates the learning of complementary features across modalities. Extensive experiments conducted on the MM-Fi and XRF55 datasets, employing six distinct modalities, demonstrate that X-Fi achieves state-of-the-art performance in human pose estimation (HPE) and human activity recognition (HAR) tasks. The findings indicate that our proposed model can efficiently support a wide range of human sensing applications, ultimately contributing to the evolution of scalable, multimodal sensing technologies.

  • 2 authors
·
Feb 16, 2025

AlignHuman: Improving Motion and Fidelity via Timestep-Segment Preference Optimization for Audio-Driven Human Animation

Recent advancements in human video generation and animation tasks, driven by diffusion models, have achieved significant progress. However, expressive and realistic human animation remains challenging due to the trade-off between motion naturalness and visual fidelity. To address this, we propose AlignHuman, a framework that combines Preference Optimization as a post-training technique with a divide-and-conquer training strategy to jointly optimize these competing objectives. Our key insight stems from an analysis of the denoising process across timesteps: (1) early denoising timesteps primarily control motion dynamics, while (2) fidelity and human structure can be effectively managed by later timesteps, even if early steps are skipped. Building on this observation, we propose timestep-segment preference optimization (TPO) and introduce two specialized LoRAs as expert alignment modules, each targeting a specific dimension in its corresponding timestep interval. The LoRAs are trained using their respective preference data and activated in the corresponding intervals during inference to enhance motion naturalness and fidelity. Extensive experiments demonstrate that AlignHuman improves strong baselines and reduces NFEs during inference, achieving a 3.3times speedup (from 100 NFEs to 30 NFEs) with minimal impact on generation quality. Homepage: https://alignhuman.github.io/{https://alignhuman.github.io/}

  • 7 authors
·
Jun 11, 2025

HumanRefiner: Benchmarking Abnormal Human Generation and Refining with Coarse-to-fine Pose-Reversible Guidance

Text-to-image diffusion models have significantly advanced in conditional image generation. However, these models usually struggle with accurately rendering images featuring humans, resulting in distorted limbs and other anomalies. This issue primarily stems from the insufficient recognition and evaluation of limb qualities in diffusion models. To address this issue, we introduce AbHuman, the first large-scale synthesized human benchmark focusing on anatomical anomalies. This benchmark consists of 56K synthesized human images, each annotated with detailed, bounding-box level labels identifying 147K human anomalies in 18 different categories. Based on this, the recognition of human anomalies can be established, which in turn enhances image generation through traditional techniques such as negative prompting and guidance. To further boost the improvement, we propose HumanRefiner, a novel plug-and-play approach for the coarse-to-fine refinement of human anomalies in text-to-image generation. Specifically, HumanRefiner utilizes a self-diagnostic procedure to detect and correct issues related to both coarse-grained abnormal human poses and fine-grained anomaly levels, facilitating pose-reversible diffusion generation. Experimental results on the AbHuman benchmark demonstrate that HumanRefiner significantly reduces generative discrepancies, achieving a 2.9x improvement in limb quality compared to the state-of-the-art open-source generator SDXL and a 1.4x improvement over DALL-E 3 in human evaluations. Our data and code are available at https://github.com/Enderfga/HumanRefiner.

  • 8 authors
·
Jul 9, 2024 1

PPGFlowECG: Latent Rectified Flow with Cross-Modal Encoding for PPG-Guided ECG Generation and Cardiovascular Disease Detection

In clinical practice, electrocardiography (ECG) remains the gold standard for cardiac monitoring, providing crucial insights for diagnosing a wide range of cardiovascular diseases (CVDs). However, its reliance on specialized equipment and trained personnel limits feasibility for continuous routine monitoring. Photoplethysmography (PPG) offers accessible, continuous monitoring but lacks definitive electrophysiological information, preventing conclusive diagnosis. Generative models present a promising approach to translate PPG into clinically valuable ECG signals, yet current methods face substantial challenges, including the misalignment of physiological semantics in generative models and the complexity of modeling in high-dimensional signals. To this end, we propose PPGFlowECG, a two-stage framework that aligns PPG and ECG in a shared latent space via the CardioAlign Encoder and employs latent rectified flow to generate ECGs with high fidelity and interpretability. To the best of our knowledge, this is the first study to experiment on MCMED, a newly released clinical-grade dataset comprising over 10 million paired PPG-ECG samples from more than 118,000 emergency department visits with expert-labeled cardiovascular disease annotations. Results demonstrate the effectiveness of our method for PPG-to-ECG translation and cardiovascular disease detection. Moreover, cardiologist-led evaluations confirm that the synthesized ECGs achieve high fidelity and improve diagnostic reliability, underscoring our method's potential for real-world cardiovascular screening.

  • 9 authors
·
Sep 24, 2025

Multimodal Sleep Stage and Sleep Apnea Classification Using Vision Transformer: A Multitask Explainable Learning Approach

Sleep is an essential component of human physiology, contributing significantly to overall health and quality of life. Accurate sleep staging and disorder detection are crucial for assessing sleep quality. Studies in the literature have proposed PSG-based approaches and machine-learning methods utilizing single-modality signals. However, existing methods often lack multimodal, multilabel frameworks and address sleep stages and disorders classification separately. In this paper, we propose a 1D-Vision Transformer for simultaneous classification of sleep stages and sleep disorders. Our method exploits the sleep disorders' correlation with specific sleep stage patterns and performs a simultaneous identification of a sleep stage and sleep disorder. The model is trained and tested using multimodal-multilabel sensory data (including photoplethysmogram, respiratory flow, and respiratory effort signals). The proposed method shows an overall accuracy (cohen's Kappa) of 78% (0.66) for five-stage sleep classification and 74% (0.58) for sleep apnea classification. Moreover, we analyzed the encoder attention weights to clarify our models' predictions and investigate the influence different features have on the models' outputs. The result shows that identified patterns, such as respiratory troughs and peaks, make a higher contribution to the final classification process.

  • 6 authors
·
Feb 18, 2025

MVHumanNet++: A Large-scale Dataset of Multi-view Daily Dressing Human Captures with Richer Annotations for 3D Human Digitization

In this era, the success of large language models and text-to-image models can be attributed to the driving force of large-scale datasets. However, in the realm of 3D vision, while significant progress has been achieved in object-centric tasks through large-scale datasets like Objaverse and MVImgNet, human-centric tasks have seen limited advancement, largely due to the absence of a comparable large-scale human dataset. To bridge this gap, we present MVHumanNet++, a dataset that comprises multi-view human action sequences of 4,500 human identities. The primary focus of our work is on collecting human data that features a large number of diverse identities and everyday clothing using multi-view human capture systems, which facilitates easily scalable data collection. Our dataset contains 9,000 daily outfits, 60,000 motion sequences and 645 million frames with extensive annotations, including human masks, camera parameters, 2D and 3D keypoints, SMPL/SMPLX parameters, and corresponding textual descriptions. Additionally, the proposed MVHumanNet++ dataset is enhanced with newly processed normal maps and depth maps, significantly expanding its applicability and utility for advanced human-centric research. To explore the potential of our proposed MVHumanNet++ dataset in various 2D and 3D visual tasks, we conducted several pilot studies to demonstrate the performance improvements and effective applications enabled by the scale provided by MVHumanNet++. As the current largest-scale 3D human dataset, we hope that the release of MVHumanNet++ dataset with annotations will foster further innovations in the domain of 3D human-centric tasks at scale. MVHumanNet++ is publicly available at https://kevinlee09.github.io/research/MVHumanNet++/.

  • 8 authors
·
May 3, 2025

CrossLoco: Human Motion Driven Control of Legged Robots via Guided Unsupervised Reinforcement Learning

Human motion driven control (HMDC) is an effective approach for generating natural and compelling robot motions while preserving high-level semantics. However, establishing the correspondence between humans and robots with different body structures is not straightforward due to the mismatches in kinematics and dynamics properties, which causes intrinsic ambiguity to the problem. Many previous algorithms approach this motion retargeting problem with unsupervised learning, which requires the prerequisite skill sets. However, it will be extremely costly to learn all the skills without understanding the given human motions, particularly for high-dimensional robots. In this work, we introduce CrossLoco, a guided unsupervised reinforcement learning framework that simultaneously learns robot skills and their correspondence to human motions. Our key innovation is to introduce a cycle-consistency-based reward term designed to maximize the mutual information between human motions and robot states. We demonstrate that the proposed framework can generate compelling robot motions by translating diverse human motions, such as running, hopping, and dancing. We quantitatively compare our CrossLoco against the manually engineered and unsupervised baseline algorithms along with the ablated versions of our framework and demonstrate that our method translates human motions with better accuracy, diversity, and user preference. We also showcase its utility in other applications, such as synthesizing robot movements from language input and enabling interactive robot control.

  • 5 authors
·
Sep 29, 2023

From Centerlines to Hemodynamics: Anisotropic RBF Decoders for Coronary Arteries

Accurate and rapid estimation of hemodynamic metrics, such as pressure and wall shear stress (WSS), is important for assessing the severity of Coronary Artery Disease (CAD). Existing approaches, including invasive Fractional Flow Reserve (FFR) measurements and computationally expensive Computational Fluid Dynamics (CFD) simulations, face challenges in invasiveness, cost, and speed. We present a framework for fast, non-invasive coronary hemodynamics prediction. The model encodes 1D vessel centerlines together with inlet flow rate using a transformer-based encoder, and predicts continuous wall-based fields via an anisotropic Radial Basis Function (RBF) decoder aligned with vessel morphology. To support training and evaluation, we introduce two datasets with paired steady-state OpenFOAM simulations: (i) a synthetic benchmark of 4,200 single-vessel geometries with controlled anatomical variations, and (ii) a multi-vessel dataset derived from ImageCAS including 4,800 cases spanning both right and left coronary arteries, generated by randomly introducing stenoses and varying physiologically plausible flow rates. Across both datasets, our method achieves lower pressure and WSS errors than strong neural-operator baselines (GNOT, Transolver, and ONO) at a fraction of the computational cost of CFD. On the multi-vessel dataset, using 1,024 anisotropic RBF centers our model reduces the mean relative L2 error by 52% compared to the best neural-operator baseline, while at 128 centers it requires 13.8x fewer FLOPs than GNOT and still outperforms all baselines. The single-vessel dataset is publicly available at https://huggingface.co/datasets/angioinsight/single-vessel-flow.

  • 3 authors
·
May 25

ROOM: A Physics-Based Continuum Robot Simulator for Photorealistic Medical Datasets Generation

Continuum robots are advancing bronchoscopy procedures by accessing complex lung airways and enabling targeted interventions. However, their development is limited by the lack of realistic training and test environments: Real data is difficult to collect due to ethical constraints and patient safety concerns, and developing autonomy algorithms requires realistic imaging and physical feedback. We present ROOM (Realistic Optical Observation in Medicine), a comprehensive simulation framework designed for generating photorealistic bronchoscopy training data. By leveraging patient CT scans, our pipeline renders multi-modal sensor data including RGB images with realistic noise and light specularities, metric depth maps, surface normals, optical flow and point clouds at medically relevant scales. We validate the data generated by ROOM in two canonical tasks for medical robotics -- multi-view pose estimation and monocular depth estimation, demonstrating diverse challenges that state-of-the-art methods must overcome to transfer to these medical settings. Furthermore, we show that the data produced by ROOM can be used to fine-tune existing depth estimation models to overcome these challenges, also enabling other downstream applications such as navigation. We expect that ROOM will enable large-scale data generation across diverse patient anatomies and procedural scenarios that are challenging to capture in clinical settings. Code and data: https://github.com/iamsalvatore/room.

  • 7 authors
·
Sep 16, 2025 2

UniVAD: A Training-free Unified Model for Few-shot Visual Anomaly Detection

Visual Anomaly Detection (VAD) aims to identify abnormal samples in images that deviate from normal patterns, covering multiple domains, including industrial, logical, and medical fields. Due to the domain gaps between these fields, existing VAD methods are typically tailored to each domain, with specialized detection techniques and model architectures that are difficult to generalize across different domains. Moreover, even within the same domain, current VAD approaches often follow a "one-category-one-model" paradigm, requiring large amounts of normal samples to train class-specific models, resulting in poor generalizability and hindering unified evaluation across domains. To address this issue, we propose a generalized few-shot VAD method, UniVAD, capable of detecting anomalies across various domains, such as industrial, logical, and medical anomalies, with a training-free unified model. UniVAD only needs few normal samples as references during testing to detect anomalies in previously unseen objects, without training on the specific domain. Specifically, UniVAD employs a Contextual Component Clustering (C^3) module based on clustering and vision foundation models to segment components within the image accurately, and leverages Component-Aware Patch Matching (CAPM) and Graph-Enhanced Component Modeling (GECM) modules to detect anomalies at different semantic levels, which are aggregated to produce the final detection result. We conduct experiments on nine datasets spanning industrial, logical, and medical fields, and the results demonstrate that UniVAD achieves state-of-the-art performance in few-shot anomaly detection tasks across multiple domains, outperforming domain-specific anomaly detection models. Code is available at https://github.com/FantasticGNU/UniVAD.

  • 6 authors
·
Dec 4, 2024

Learning Tubule-Sensitive CNNs for Pulmonary Airway and Artery-Vein Segmentation in CT

Training convolutional neural networks (CNNs) for segmentation of pulmonary airway, artery, and vein is challenging due to sparse supervisory signals caused by the severe class imbalance between tubular targets and background. We present a CNNs-based method for accurate airway and artery-vein segmentation in non-contrast computed tomography. It enjoys superior sensitivity to tenuous peripheral bronchioles, arterioles, and venules. The method first uses a feature recalibration module to make the best use of features learned from the neural networks. Spatial information of features is properly integrated to retain relative priority of activated regions, which benefits the subsequent channel-wise recalibration. Then, attention distillation module is introduced to reinforce representation learning of tubular objects. Fine-grained details in high-resolution attention maps are passing down from one layer to its previous layer recursively to enrich context. Anatomy prior of lung context map and distance transform map is designed and incorporated for better artery-vein differentiation capacity. Extensive experiments demonstrated considerable performance gains brought by these components. Compared with state-of-the-art methods, our method extracted much more branches while maintaining competitive overall segmentation performance. Codes and models are available at http://www.pami.sjtu.edu.cn/News/56

  • 9 authors
·
Dec 10, 2020

Aortic Valve Disease Detection from PPG via Physiology-Informed Self-Supervised Learning

Traditional diagnosis of aortic valve disease relies on echocardiography, but its cost and required expertise limit its use in large-scale early screening. Photoplethysmography (PPG) has emerged as a promising screening modality due to its widespread availability in wearable devices and its ability to reflect underlying hemodynamic dynamics. However, the extreme scarcity of gold-standard labeled PPG data severely constrains the effectiveness of data-driven approaches. To address this challenge, we propose and validate a new paradigm, Physiology-Guided Self-Supervised Learning (PG-SSL), aimed at unlocking the value of large-scale unlabeled PPG data for efficient screening of Aortic Stenosis (AS) and Aortic Regurgitation (AR). Using over 170,000 unlabeled PPG samples from the UK Biobank, we formalize clinical knowledge into a set of PPG morphological phenotypes and construct a pulse pattern recognition proxy task for self-supervised pre-training. A dual-branch, gated-fusion architecture is then employed for efficient fine-tuning on a small labeled subset. The proposed PG-SSL framework achieves AUCs of 0.765 and 0.776 for AS and AR screening, respectively, significantly outperforming supervised baselines trained on limited labeled data. Multivariable analysis further validates the model output as an independent digital biomarker with sustained prognostic value after adjustment for standard clinical risk factors. This study demonstrates that PG-SSL provides an effective, domain knowledge-driven solution to label scarcity in medical artificial intelligence and shows strong potential for enabling low-cost, large-scale early screening of aortic valve disease.

  • 7 authors
·
Feb 3

DreamID-Omni: Unified Framework for Controllable Human-Centric Audio-Video Generation

Recent advancements in foundation models have revolutionized joint audio-video generation. However, existing approaches typically treat human-centric tasks including reference-based audio-video generation (R2AV), video editing (RV2AV) and audio-driven video animation (RA2V) as isolated objectives. Furthermore, achieving precise, disentangled control over multiple character identities and voice timbres within a single framework remains an open challenge. In this paper, we propose DreamID-Omni, a unified framework for controllable human-centric audio-video generation. Specifically, we design a Symmetric Conditional Diffusion Transformer that integrates heterogeneous conditioning signals via a symmetric conditional injection scheme. To resolve the pervasive identity-timbre binding failures and speaker confusion in multi-person scenarios, we introduce a Dual-Level Disentanglement strategy: Synchronized RoPE at the signal level to ensure rigid attention-space binding, and Structured Captions at the semantic level to establish explicit attribute-subject mappings. Furthermore, we devise a Multi-Task Progressive Training scheme that leverages weakly-constrained generative priors to regularize strongly-constrained tasks, preventing overfitting and harmonizing disparate objectives. Extensive experiments demonstrate that DreamID-Omni achieves comprehensive state-of-the-art performance across video, audio, and audio-visual consistency, even outperforming leading proprietary commercial models. We will release our code to bridge the gap between academic research and commercial-grade applications.

ByteDance ByteDance
·
Feb 12 5

Just Dance with π! A Poly-modal Inductor for Weakly-supervised Video Anomaly Detection

Weakly-supervised methods for video anomaly detection (VAD) are conventionally based merely on RGB spatio-temporal features, which continues to limit their reliability in real-world scenarios. This is due to the fact that RGB-features are not sufficiently distinctive in setting apart categories such as shoplifting from visually similar events. Therefore, towards robust complex real-world VAD, it is essential to augment RGB spatio-temporal features by additional modalities. Motivated by this, we introduce the Poly-modal Induced framework for VAD: "PI-VAD", a novel approach that augments RGB representations by five additional modalities. Specifically, the modalities include sensitivity to fine-grained motion (Pose), three dimensional scene and entity representation (Depth), surrounding objects (Panoptic masks), global motion (optical flow), as well as language cues (VLM). Each modality represents an axis of a polygon, streamlined to add salient cues to RGB. PI-VAD includes two plug-in modules, namely Pseudo-modality Generation module and Cross Modal Induction module, which generate modality-specific prototypical representation and, thereby, induce multi-modal information into RGB cues. These modules operate by performing anomaly-aware auxiliary tasks and necessitate five modality backbones -- only during training. Notably, PI-VAD achieves state-of-the-art accuracy on three prominent VAD datasets encompassing real-world scenarios, without requiring the computational overhead of five modality backbones at inference.

  • 8 authors
·
May 19, 2025

ALPHA: AnomaLous Physiological Health Assessment Using Large Language Models

This study concentrates on evaluating the efficacy of Large Language Models (LLMs) in healthcare, with a specific focus on their application in personal anomalous health monitoring. Our research primarily investigates the capabilities of LLMs in interpreting and analyzing physiological data obtained from FDA-approved devices. We conducted an extensive analysis using anomalous physiological data gathered in a simulated low-air-pressure plateau environment. This allowed us to assess the precision and reliability of LLMs in understanding and evaluating users' health status with notable specificity. Our findings reveal that LLMs exhibit exceptional performance in determining medical indicators, including a Mean Absolute Error (MAE) of less than 1 beat per minute for heart rate and less than 1% for oxygen saturation (SpO2). Furthermore, the Mean Absolute Percentage Error (MAPE) for these evaluations remained below 1%, with the overall accuracy of health assessments surpassing 85%. In image analysis tasks, such as interpreting photoplethysmography (PPG) data, our specially adapted GPT models demonstrated remarkable proficiency, achieving less than 1 bpm error in cycle count and 7.28 MAE for heart rate estimation. This study highlights LLMs' dual role as health data analysis tools and pivotal elements in advanced AI health assistants, offering personalized health insights and recommendations within the future health assistant framework.

  • 7 authors
·
Nov 21, 2023

Toward World Modeling of Physiological Signals with Chaos-Theoretic Balancing and Latent Dynamics

Physiological time series signals reflect complex, multi-scale dynamical processes of the human body. Existing modeling studies focus on static tasks such as classification, event forecasting, or short-horizon next step prediction, while long-horizon signal-level forecasting and predictive nature of physiological signals remain underexplored. We introduce NormWear-2, a world model that encodes both multivariate physiological signals and clinical intervention variables into a shared latent space and models their joint temporal evolution as a dynamical system. Our approach combines inference from prior pre-trained knowledge (intuition) with instant non-parametric latent state transition adaptation (insight), enabling coherent forecasting across multiple temporal scales, conditioned on heterogeneous clinical interventions. During the pretraining phase, we find that chaos-theoretic balancing of dynamical regime diversity yields more robust representations, with a smaller balanced corpus outperforming one twice its size and capturing bifurcation regimes. We evaluate the world model performance across diverse real-world physiological datasets spanning heterogeneous temporal resolutions and intervention regimes, covering daily life, point-of-care, and clinical settings, including fitness planning, hemodialysis, diabetes management, and surgical monitoring. These evaluation datasets comprise records from 8,026 subjects, spanning study durations from 3.2 hours for high-resolution signal data to 2.3 years for longitudinal clinical biomarker tracking. NormWear-2 achieves the best overall forecasting performance across time, frequency, and latent representation domains, with significant improvements over state-of-the-art time series foundation models, while maintaining competitive downstream representation quality, providing a step toward general-purpose world models for physiological signals.

  • 11 authors
·
May 13

Autonomous Multi-Modal LLM Agents for Treatment Planning in Focused Ultrasound Ablation Surgery

Focused Ultrasound Ablation Surgery (FUAS) has emerged as a promising non-invasive therapeutic modality, valued for its safety and precision. Nevertheless, its clinical implementation entails intricate tasks such as multimodal image interpretation, personalized dose planning, and real-time intraoperative decision-making processes that demand intelligent assistance to improve efficiency and reliability. We introduce FUAS-Agents, an autonomous agent system that leverages the multimodal understanding and tool-using capabilities of large language models (LLMs). By integrating patient profiles and MRI data, FUAS-Agents orchestrates a suite of specialized medical AI tools, including segmentation, treatment dose prediction, and clinical guideline retrieval, to generate personalized treatment plans comprising MRI image, dose parameters, and therapeutic strategies. We evaluate the system in a uterine fibroid treatment scenario. Human assessment by four senior FUAS experts indicates that 82.5%, 82.5%, 87.5%, and 97.5% of the generated plans were rated 4 or above (on a 5-point scale) in terms of completeness, accuracy, fluency, and clinical compliance, respectively. These results demonstrate the potential of LLM-driven agents in enhancing decision-making across complex clinical workflows, and exemplify a translational paradigm that combines general-purpose models with specialized expert systems to solve practical challenges in vertical healthcare domains.

  • 9 authors
·
May 27, 2025

A Hybrid Deep Learning Model for Robust Biometric Authentication from Low-Frame-Rate PPG Signals

Photoplethysmography (PPG) signals, which measure changes in blood volume in the skin using light, have recently gained attention in biometric authentication because of their non-invasive acquisition, inherent liveness detection, and suitability for low-cost wearable devices. However, PPG signal quality is challenged by motion artifacts, illumination changes, and inter-subject physiological variability, making robust feature extraction and classification crucial. This study proposes a lightweight and cost-effective biometric authentication framework based on PPG signals extracted from low-frame-rate fingertip videos. The CFIHSR dataset, comprising PPG recordings from 46 subjects at a sampling rate of 14 Hz, is employed for evaluation. The raw PPG signals undergo a standard preprocessing pipeline involving baseline drift removal, motion artifact suppression using Principal Component Analysis (PCA), bandpass filtering, Fourier-based resampling, and amplitude normalization. To generate robust representations, each one-dimensional PPG segment is converted into a two-dimensional time-frequency scalogram via the Continuous Wavelet Transform (CWT), effectively capturing transient cardiovascular dynamics. We developed a hybrid deep learning model, termed CVT-ConvMixer-LSTM, by combining spatial features from the Convolutional Vision Transformer (CVT) and ConvMixer branches with temporal features from a Long Short-Term Memory network (LSTM). The experimental results on 46 subjects demonstrate an authentication accuracy of 98%, validating the robustness of the model to noise and variability between subjects. Due to its efficiency, scalability, and inherent liveness detection capability, the proposed system is well-suited for real-world mobile and embedded biometric security applications.

  • 2 authors
·
Nov 5, 2025

PVminer: A Domain-Specific Tool to Detect the Patient Voice in Patient Generated Data

Patient-generated text such as secure messages, surveys, and interviews contains rich expressions of the patient voice (PV), reflecting communicative behaviors and social determinants of health (SDoH). Traditional qualitative coding frameworks are labor intensive and do not scale to large volumes of patient-authored messages across health systems. Existing machine learning (ML) and natural language processing (NLP) approaches provide partial solutions but often treat patient-centered communication (PCC) and SDoH as separate tasks or rely on models not well suited to patient-facing language. We introduce PVminer, a domain-adapted NLP framework for structuring patient voice in secure patient-provider communication. PVminer formulates PV detection as a multi-label, multi-class prediction task integrating patient-specific BERT encoders (PV-BERT-base and PV-BERT-large), unsupervised topic modeling for thematic augmentation (PV-Topic-BERT), and fine-tuned classifiers for Code, Subcode, and Combo-level labels. Topic representations are incorporated during fine-tuning and inference to enrich semantic inputs. PVminer achieves strong performance across hierarchical tasks and outperforms biomedical and clinical pre-trained baselines, achieving F1 scores of 82.25% (Code), 80.14% (Subcode), and up to 77.87% (Combo). An ablation study further shows that author identity and topic-based augmentation each contribute meaningful gains. Pre-trained models, source code, and documentation will be publicly released, with annotated datasets available upon request for research use.

  • 9 authors
·
Feb 24

Learn to Sing by Listening: Building Controllable Virtual Singer by Unsupervised Learning from Voice Recordings

The virtual world is being established in which digital humans are created indistinguishable from real humans. Producing their audio-related capabilities is crucial since voice conveys extensive personal characteristics. We aim to create a controllable audio-form virtual singer; however, supervised modeling and controlling all different factors of the singing voice, such as timbre, tempo, pitch, and lyrics, is extremely difficult since accurately labeling all such information needs enormous labor work. In this paper, we propose a framework that could digitize a person's voice by simply "listening" to the clean voice recordings of any content in a fully unsupervised manner and predict singing voices even only using speaking recordings. A variational auto-encoder (VAE) based framework is developed, which leverages a set of pre-trained models to encode the audio as various hidden embeddings representing different factors of the singing voice, and further decodes the embeddings into raw audio. By manipulating the hidden embeddings for different factors, the resulting singing voices can be controlled, and new virtual singers can also be further generated by interpolating between timbres. Evaluations of different types of experiments demonstrate the proposed method's effectiveness. The proposed method is the critical technique for producing the AI choir, which empowered the human-AI symbiotic orchestra in Hong Kong in July 2022.

  • 4 authors
·
May 9, 2023

Large-scale Training of Foundation Models for Wearable Biosignals

Tracking biosignals is crucial for monitoring wellness and preempting the development of severe medical conditions. Today, wearable devices can conveniently record various biosignals, creating the opportunity to monitor health status without disruption to one's daily routine. Despite widespread use of wearable devices and existing digital biomarkers, the absence of curated data with annotated medical labels hinders the development of new biomarkers to measure common health conditions. In fact, medical datasets are usually small in comparison to other domains, which is an obstacle for developing neural network models for biosignals. To address this challenge, we have employed self-supervised learning using the unlabeled sensor data collected under informed consent from the large longitudinal Apple Heart and Movement Study (AHMS) to train foundation models for two common biosignals: photoplethysmography (PPG) and electrocardiogram (ECG) recorded on Apple Watch. We curated PPG and ECG datasets from AHMS that include data from ~141K participants spanning ~3 years. Our self-supervised learning framework includes participant level positive pair selection, stochastic augmentation module and a regularized contrastive loss optimized with momentum training, and generalizes well to both PPG and ECG modalities. We show that the pre-trained foundation models readily encode information regarding participants' demographics and health conditions. To the best of our knowledge, this is the first study that builds foundation models using large-scale PPG and ECG data collected via wearable consumer devices x2013 prior works have commonly used smaller-size datasets collected in clinical and experimental settings. We believe PPG and ECG foundation models can enhance future wearable devices by reducing the reliance on labeled data and hold the potential to help the users improve their health.

  • 6 authors
·
Dec 8, 2023

Affective social anthropomorphic intelligent system

Human conversational styles are measured by the sense of humor, personality, and tone of voice. These characteristics have become essential for conversational intelligent virtual assistants. However, most of the state-of-the-art intelligent virtual assistants (IVAs) are failed to interpret the affective semantics of human voices. This research proposes an anthropomorphic intelligent system that can hold a proper human-like conversation with emotion and personality. A voice style transfer method is also proposed to map the attributes of a specific emotion. Initially, the frequency domain data (Mel-Spectrogram) is created by converting the temporal audio wave data, which comprises discrete patterns for audio features such as notes, pitch, rhythm, and melody. A collateral CNN-Transformer-Encoder is used to predict seven different affective states from voice. The voice is also fed parallelly to the deep-speech, an RNN model that generates the text transcription from the spectrogram. Then the transcripted text is transferred to the multi-domain conversation agent using blended skill talk, transformer-based retrieve-and-generate generation strategy, and beam-search decoding, and an appropriate textual response is generated. The system learns an invertible mapping of data to a latent space that can be manipulated and generates a Mel-spectrogram frame based on previous Mel-spectrogram frames to voice synthesize and style transfer. Finally, the waveform is generated using WaveGlow from the spectrogram. The outcomes of the studies we conducted on individual models were auspicious. Furthermore, users who interacted with the system provided positive feedback, demonstrating the system's effectiveness.

  • 5 authors
·
Apr 19, 2023

SmartHome-Bench: A Comprehensive Benchmark for Video Anomaly Detection in Smart Homes Using Multi-Modal Large Language Models

Video anomaly detection (VAD) is essential for enhancing safety and security by identifying unusual events across different environments. Existing VAD benchmarks, however, are primarily designed for general-purpose scenarios, neglecting the specific characteristics of smart home applications. To bridge this gap, we introduce SmartHome-Bench, the first comprehensive benchmark specially designed for evaluating VAD in smart home scenarios, focusing on the capabilities of multi-modal large language models (MLLMs). Our newly proposed benchmark consists of 1,203 videos recorded by smart home cameras, organized according to a novel anomaly taxonomy that includes seven categories, such as Wildlife, Senior Care, and Baby Monitoring. Each video is meticulously annotated with anomaly tags, detailed descriptions, and reasoning. We further investigate adaptation methods for MLLMs in VAD, assessing state-of-the-art closed-source and open-source models with various prompting techniques. Results reveal significant limitations in the current models' ability to detect video anomalies accurately. To address these limitations, we introduce the Taxonomy-Driven Reflective LLM Chain (TRLC), a new LLM chaining framework that achieves a notable 11.62% improvement in detection accuracy. The benchmark dataset and code are publicly available at https://github.com/Xinyi-0724/SmartHome-Bench-LLM.

  • 7 authors
·
Jun 15, 2025

Multi-site, Multi-domain Airway Tree Modeling (ATM'22): A Public Benchmark for Pulmonary Airway Segmentation

Open international challenges are becoming the de facto standard for assessing computer vision and image analysis algorithms. In recent years, new methods have extended the reach of pulmonary airway segmentation that is closer to the limit of image resolution. Since EXACT'09 pulmonary airway segmentation, limited effort has been directed to quantitative comparison of newly emerged algorithms driven by the maturity of deep learning based approaches and clinical drive for resolving finer details of distal airways for early intervention of pulmonary diseases. Thus far, public annotated datasets are extremely limited, hindering the development of data-driven methods and detailed performance evaluation of new algorithms. To provide a benchmark for the medical imaging community, we organized the Multi-site, Multi-domain Airway Tree Modeling (ATM'22), which was held as an official challenge event during the MICCAI 2022 conference. ATM'22 provides large-scale CT scans with detailed pulmonary airway annotation, including 500 CT scans (300 for training, 50 for validation, and 150 for testing). The dataset was collected from different sites and it further included a portion of noisy COVID-19 CTs with ground-glass opacity and consolidation. Twenty-three teams participated in the entire phase of the challenge and the algorithms for the top ten teams are reviewed in this paper. Quantitative and qualitative results revealed that deep learning models embedded with the topological continuity enhancement achieved superior performance in general. ATM'22 challenge holds as an open-call design, the training data and the gold standard evaluation are available upon successful registration via its homepage.

  • 36 authors
·
Jun 26, 2023

Frequency-Guided Diffusion Model with Perturbation Training for Skeleton-Based Video Anomaly Detection

Video anomaly detection (VAD) is a vital yet complex open-set task in computer vision, commonly tackled through reconstruction-based methods. However, these methods struggle with two key limitations: (1) insufficient robustness in open-set scenarios, where unseen normal motions are frequently misclassified as anomalies, and (2) an overemphasis on, but restricted capacity for, local motion reconstruction, which are inherently difficult to capture accurately due to their diversity. To overcome these challenges, we introduce a novel frequency-guided diffusion model with perturbation training. First, we enhance robustness by training a generator to produce perturbed samples, which are similar to normal samples and target the weakness of the reconstruction model. This training paradigm expands the reconstruction domain of the model, improving its generalization to unseen normal motions. Second, to address the overemphasis on motion details, we employ the 2D Discrete Cosine Transform (DCT) to separate high-frequency (local) and low-frequency (global) motion components. By guiding the diffusion model with observed high-frequency information, we prioritize the reconstruction of low-frequency components, enabling more accurate and robust anomaly detection. Extensive experiments on five widely used VAD datasets demonstrate that our approach surpasses state-of-the-art methods, underscoring its effectiveness in open-set scenarios and diverse motion contexts. Our project website is https://xiaofeng-tan.github.io/projects/FG-Diff/index.html.

  • 4 authors
·
Dec 4, 2024

EchoWorld: Learning Motion-Aware World Models for Echocardiography Probe Guidance

Echocardiography is crucial for cardiovascular disease detection but relies heavily on experienced sonographers. Echocardiography probe guidance systems, which provide real-time movement instructions for acquiring standard plane images, offer a promising solution for AI-assisted or fully autonomous scanning. However, developing effective machine learning models for this task remains challenging, as they must grasp heart anatomy and the intricate interplay between probe motion and visual signals. To address this, we present EchoWorld, a motion-aware world modeling framework for probe guidance that encodes anatomical knowledge and motion-induced visual dynamics, while effectively leveraging past visual-motion sequences to enhance guidance precision. EchoWorld employs a pre-training strategy inspired by world modeling principles, where the model predicts masked anatomical regions and simulates the visual outcomes of probe adjustments. Built upon this pre-trained model, we introduce a motion-aware attention mechanism in the fine-tuning stage that effectively integrates historical visual-motion data, enabling precise and adaptive probe guidance. Trained on more than one million ultrasound images from over 200 routine scans, EchoWorld effectively captures key echocardiographic knowledge, as validated by qualitative analysis. Moreover, our method significantly reduces guidance errors compared to existing visual backbones and guidance frameworks, excelling in both single-frame and sequential evaluation protocols. Code is available at https://github.com/LeapLabTHU/EchoWorld.

  • 6 authors
·
Apr 17, 2025

SilentWear: an Ultra-Low Power Wearable System for EMG-based Silent Speech Recognition

Detecting speech from biosignals is gaining increasing attention due to the potential to develop human-computer interfaces that are noise-robust, privacy-preserving, and scalable for both clinical applications and daily use. However, most existing approaches remain limited by insufficient wearability and the lack of edge-processing capabilities, which are essential for minimally obtrusive, responsive, and private assistive technologies. In this work, we present SilentWear, a fully wearable, textile-based neck interface for EMG signal acquisition and processing. Powered by BioGAP-Ultra, the system enables end-to-end data acquisition from 14 differential channels and on-device speech recognition. SilentWear is coupled with SpeechNet, a lightweight 15k-parameter CNN architecture specifically tailored for EMG-based speech decoding, achieving an average cross-validated accuracy of 84.8pm4.6% and 77.5pm6.6% for vocalized and silent speech, respectively, over eight representative human-machine interaction commands collected over multiple days. We evaluate robustness to repositioning induced by multi-day use. In an inter-session setting, the system achieves average accuracies of 71.1pm8.3% and 59.3\pm2.2% for vocalized and silent speech, respectively. To mitigate performance degradation due to repositioning, we propose an incremental fine-tuning strategy, demonstrating more than 10% accuracy recovery with less than 10 minutes of additional user data. Finally, we demonstrate end-to-end real-time on-device speech recognition on a commercial multi-core microcontroller unit (MCU), achieving an energy consumption of 63.9μJ per inference with a latency of 2.47 ms. With a total power consumption of 20.5mW for acquisition, inference, and wireless transmission of results, SilentWear enables continuous operation for more than 27 hours.

  • 8 authors
·
Mar 3

Vascular anatomy-aware self-supervised pre-training for X-ray angiogram analysis

X-ray angiography is the gold standard imaging modality for cardiovascular diseases. However, current deep learning approaches for X-ray angiogram analysis are severely constrained by the scarcity of annotated data. While large-scale self-supervised learning (SSL) has emerged as a promising solution, its potential in this domain remains largely unexplored, primarily due to the lack of effective SSL frameworks and large-scale datasets. To bridge this gap, we introduce a vascular anatomy-aware masked image modeling (VasoMIM) framework that explicitly integrates domain-specific anatomical knowledge. Specifically, VasoMIM comprises two key designs: an anatomy-guided masking strategy and an anatomical consistency loss. The former strategically masks vessel-containing patches to compel the model to learn robust vascular semantics, while the latter preserves structural consistency of vessels between original and reconstructed images, enhancing the discriminability of the learned representations. In conjunction with VasoMIM, we curate XA-170K, the largest X-ray angiogram pre-training dataset to date. We validate VasoMIM on four downstream tasks across six datasets, where it demonstrates superior transferability and achieves state-of-the-art performance compared to existing methods. These findings highlight the significant potential of VasoMIM as a foundation model for advancing a wide range of X-ray angiogram analysis tasks. VasoMIM and XA-170K will be available at https://github.com/Dxhuang-CASIA/XA-SSL.

  • 11 authors
·
Feb 11

QualityFM: a Multimodal Physiological Signal Foundation Model with Self-Distillation for Signal Quality Challenges in Critically Ill Patients

Photoplethysmogram (PPG) and electrocardiogram (ECG) are commonly recorded in intesive care unit (ICU) and operating room (OR). However, the high incidence of poor, incomplete, and inconsistent signal quality, can lead to false alarms or diagnostic inaccuracies. The methods explored so far suffer from limited generalizability, reliance on extensive labeled data, and poor cross-task transferability. To overcome these challenges, we introduce QualityFM, a novel multimodal foundation model for these physiological signals, designed to acquire a general-purpose understanding of signal quality. Our model is pre-trained on an large-scale dataset comprising over 21 million 30-second waveforms and 179,757 hours of data. Our approach involves a dual-track architecture that processes paired physiological signals of differing quality, leveraging a self-distillation strategy where an encoder for high-quality signals is used to guide the training of an encoder for low-quality signals. To efficiently handle long sequential signals and capture essential local quasi-periodic patterns, we integrate a windowed sparse attention mechanism within our Transformer-based model. Furthermore, a composite loss function, which combines direct distillation loss on encoder outputs with indirect reconstruction loss based on power and phase spectra, ensures the preservation of frequency-domain characteristics of the signals. We pre-train three models with varying parameter counts (9.6 M to 319 M) and demonstrate their efficacy and practical value through transfer learning on three distinct clinical tasks: false alarm of ventricular tachycardia detection, the identification of atrial fibrillation and the estimation of arterial blood pressure (ABP) from PPG and ECG signals.

  • 3 authors
·
Sep 8, 2025

Deceptive-Human: Prompt-to-NeRF 3D Human Generation with 3D-Consistent Synthetic Images

This paper presents Deceptive-Human, a novel Prompt-to-NeRF framework capitalizing state-of-the-art control diffusion models (e.g., ControlNet) to generate a high-quality controllable 3D human NeRF. Different from direct 3D generative approaches, e.g., DreamFusion and DreamHuman, Deceptive-Human employs a progressive refinement technique to elevate the reconstruction quality. This is achieved by utilizing high-quality synthetic human images generated through the ControlNet with view-consistent loss. Our method is versatile and readily extensible, accommodating multimodal inputs, including a text prompt and additional data such as 3D mesh, poses, and seed images. The resulting 3D human NeRF model empowers the synthesis of highly photorealistic novel views from 360-degree perspectives. The key to our Deceptive-Human for hallucinating multi-view consistent synthetic human images lies in our progressive finetuning strategy. This strategy involves iteratively enhancing views using the provided multimodal inputs at each intermediate step to improve the human NeRF model. Within this iterative refinement process, view-dependent appearances are systematically eliminated to prevent interference with the underlying density estimation. Extensive qualitative and quantitative experimental comparison shows that our deceptive human models achieve state-of-the-art application quality.

  • 4 authors
·
Nov 27, 2023

Human Vision Constrained Super-Resolution

Modern deep-learning super-resolution (SR) techniques process images and videos independently of the underlying content and viewing conditions. However, the sensitivity of the human visual system (HVS) to image details changes depending on the underlying image characteristics, such as spatial frequency, luminance, color, contrast, or motion; as well viewing condition aspects such as ambient lighting and distance to the display. This observation suggests that computational resources spent on up-sampling images/videos may be wasted whenever a viewer cannot resolve the synthesized details i.e the resolution of details exceeds the resolving capability of human vision. Motivated by this observation, we propose a human vision inspired and architecture-agnostic approach for controlling SR techniques to deliver visually optimal results while limiting computational complexity. Its core is an explicit Human Visual Processing Framework (HVPF) that dynamically and locally guides SR methods according to human sensitivity to specific image details and viewing conditions. We demonstrate the application of our framework in combination with network branching to improve the computational efficiency of SR methods. Quantitative and qualitative evaluations, including user studies, demonstrate the effectiveness of our approach in reducing FLOPS by factors of 2times and greater, without sacrificing perceived quality.

MV-Performer: Taming Video Diffusion Model for Faithful and Synchronized Multi-view Performer Synthesis

Recent breakthroughs in video generation, powered by large-scale datasets and diffusion techniques, have shown that video diffusion models can function as implicit 4D novel view synthesizers. Nevertheless, current methods primarily concentrate on redirecting camera trajectory within the front view while struggling to generate 360-degree viewpoint changes. In this paper, we focus on human-centric subdomain and present MV-Performer, an innovative framework for creating synchronized novel view videos from monocular full-body captures. To achieve a 360-degree synthesis, we extensively leverage the MVHumanNet dataset and incorporate an informative condition signal. Specifically, we use the camera-dependent normal maps rendered from oriented partial point clouds, which effectively alleviate the ambiguity between seen and unseen observations. To maintain synchronization in the generated videos, we propose a multi-view human-centric video diffusion model that fuses information from the reference video, partial rendering, and different viewpoints. Additionally, we provide a robust inference procedure for in-the-wild video cases, which greatly mitigates the artifacts induced by imperfect monocular depth estimation. Extensive experiments on three datasets demonstrate our MV-Performer's state-of-the-art effectiveness and robustness, setting a strong model for human-centric 4D novel view synthesis.

  • 9 authors
·
Oct 8, 2025

MVD-HuGaS: Human Gaussians from a Single Image via 3D Human Multi-view Diffusion Prior

3D human reconstruction from a single image is a challenging problem and has been exclusively studied in the literature. Recently, some methods have resorted to diffusion models for guidance, optimizing a 3D representation via Score Distillation Sampling(SDS) or generating one back-view image for facilitating reconstruction. However, these methods tend to produce unsatisfactory artifacts (e.g. flattened human structure or over-smoothing results caused by inconsistent priors from multiple views) and struggle with real-world generalization in the wild. In this work, we present MVD-HuGaS, enabling free-view 3D human rendering from a single image via a multi-view human diffusion model. We first generate multi-view images from the single reference image with an enhanced multi-view diffusion model, which is well fine-tuned on high-quality 3D human datasets to incorporate 3D geometry priors and human structure priors. To infer accurate camera poses from the sparse generated multi-view images for reconstruction, an alignment module is introduced to facilitate joint optimization of 3D Gaussians and camera poses. Furthermore, we propose a depth-based Facial Distortion Mitigation module to refine the generated facial regions, thereby improving the overall fidelity of the reconstruction.Finally, leveraging the refined multi-view images, along with their accurate camera poses, MVD-HuGaS optimizes the 3D Gaussians of the target human for high-fidelity free-view renderings. Extensive experiments on Thuman2.0 and 2K2K datasets show that the proposed MVD-HuGaS achieves state-of-the-art performance on single-view 3D human rendering.

  • 8 authors
·
Mar 11, 2025

Vision Language Models in Medicine

With the advent of Vision-Language Models (VLMs), medical artificial intelligence (AI) has experienced significant technological progress and paradigm shifts. This survey provides an extensive review of recent advancements in Medical Vision-Language Models (Med-VLMs), which integrate visual and textual data to enhance healthcare outcomes. We discuss the foundational technology behind Med-VLMs, illustrating how general models are adapted for complex medical tasks, and examine their applications in healthcare. The transformative impact of Med-VLMs on clinical practice, education, and patient care is highlighted, alongside challenges such as data scarcity, narrow task generalization, interpretability issues, and ethical concerns like fairness, accountability, and privacy. These limitations are exacerbated by uneven dataset distribution, computational demands, and regulatory hurdles. Rigorous evaluation methods and robust regulatory frameworks are essential for safe integration into healthcare workflows. Future directions include leveraging large-scale, diverse datasets, improving cross-modal generalization, and enhancing interpretability. Innovations like federated learning, lightweight architectures, and Electronic Health Record (EHR) integration are explored as pathways to democratize access and improve clinical relevance. This review aims to provide a comprehensive understanding of Med-VLMs' strengths and limitations, fostering their ethical and balanced adoption in healthcare.

  • 3 authors
·
Feb 24, 2025

HumanVideo-MME: Benchmarking MLLMs for Human-Centric Video Understanding

Multimodal Large Language Models (MLLMs) have demonstrated significant advances in visual understanding tasks involving both images and videos. However, their capacity to comprehend human-centric video data remains underexplored, primarily due to the absence of comprehensive and high-quality evaluation benchmarks. Existing human-centric benchmarks predominantly emphasize video generation quality and action recognition, while overlooking essential perceptual and cognitive abilities required in human-centered scenarios. Furthermore, they are often limited by single-question paradigms and overly simplistic evaluation metrics. To address above limitations, we propose a modern HV-MMBench, a rigorously curated benchmark designed to provide a more holistic evaluation of MLLMs in human-centric video understanding. Compared to existing human-centric video benchmarks, our work offers the following key features: (1) Diverse evaluation dimensions: HV-MMBench encompasses 13 tasks, ranging from basic attribute perception (e.g., age estimation, emotion recognition) to advanced cognitive reasoning (e.g., social relationship prediction, intention prediction), enabling comprehensive assessment of model capabilities; (2) Varied data types: The benchmark includes multiple-choice, fill-in-blank, true/false, and open-ended question formats, combined with diverse evaluation metrics, to more accurately and robustly reflect model performance; (3) Multi-domain video coverage: The benchmark spans 50 distinct visual scenarios, enabling comprehensive evaluation across fine-grained scene variations; (4) Temporal coverage: The benchmark covers videos from short-term (10 seconds) to long-term (up to 30min) durations, supporting systematic analysis of models temporal reasoning abilities across diverse contextual lengths.

  • 12 authors
·
Jul 7, 2025

A Detection-Gated Pipeline for Robust Glottal Area Waveform Extraction and Clinical Pathology Assessment

Background: Accurate glottal segmentation in high-speed videoendoscopy (HSV) is essential for extracting kinematic biomarkers of laryngeal function. However, existing deep learning models often produce spurious artifacts in non-glottal frames and fail to generalize across different clinical settings. Methods: We propose a detection-gated pipeline that integrates a localizer with a segmenter. A temporal consistency wrapper ensures robustness by suppressing false positives during glottal closure and occlusion. The segmenter was trained on a limited subset of the GIRAFE dataset (600 frames), while the localizer was trained on the BAGLS training set. The in-distribution localizer provides a tight region of interest (ROI), removing geometric anatomical variations and enabling cross-dataset generalization without fine-tuning. Results: The pipeline achieved state-of-the-art performance on the GIRAFE (DSC=0.81) and BAGLS (DSC=0.85) benchmarks and demonstrated superior generalizability. Notably, the framework maintained robust cross-dataset generalization (DSC=0.77). Downstream validation on a 65-subject clinical cohort confirmed that automated kinematic features - specifically the Open Quotient and Glottal Area Waveform (GAW) - remained consistent with clinical benchmarks. The coefficient of variation (CV) of the glottal area was a significant marker for distinguishing healthy from pathological vocal function (p=0.006). Conclusions: This architecture provides a computationally efficient solution (~35 frames/s) suitable for real-time clinical use. By overcoming cross-dataset variability, this framework facilitates the standardized, large-scale extraction of clinical biomarkers across diverse endoscopy platforms. Code, trained weights, and evaluation scripts are released at https://github.com/hari-krishnan/openglottal.

  • 1 authors
·
Mar 2

Modelling Human Visual Motion Processing with Trainable Motion Energy Sensing and a Self-attention Network

Visual motion processing is essential for humans to perceive and interact with dynamic environments. Despite extensive research in cognitive neuroscience, image-computable models that can extract informative motion flow from natural scenes in a manner consistent with human visual processing have yet to be established. Meanwhile, recent advancements in computer vision (CV), propelled by deep learning, have led to significant progress in optical flow estimation, a task closely related to motion perception. Here we propose an image-computable model of human motion perception by bridging the gap between biological and CV models. Specifically, we introduce a novel two-stages approach that combines trainable motion energy sensing with a recurrent self-attention network for adaptive motion integration and segregation. This model architecture aims to capture the computations in V1-MT, the core structure for motion perception in the biological visual system, while providing the ability to derive informative motion flow for a wide range of stimuli, including complex natural scenes. In silico neurophysiology reveals that our model's unit responses are similar to mammalian neural recordings regarding motion pooling and speed tuning. The proposed model can also replicate human responses to a range of stimuli examined in past psychophysical studies. The experimental results on the Sintel benchmark demonstrate that our model predicts human responses better than the ground truth, whereas the state-of-the-art CV models show the opposite. Our study provides a computational architecture consistent with human visual motion processing, although the physiological correspondence may not be exact.

  • 4 authors
·
May 16, 2023

A Unit Enhancement and Guidance Framework for Audio-Driven Avatar Video Generation

Audio-driven human animation technology is widely used in human-computer interaction, and the emergence of diffusion models has further advanced its development. Currently, most methods rely on multi-stage generation and intermediate representations, resulting in long inference time and issues with generation quality in specific foreground regions and audio-motion consistency. These shortcomings are primarily due to the lack of localized fine-grained supervised guidance. To address above challenges, we propose Parts-aware Audio-driven Human Animation, PAHA, a unit enhancement and guidance framework for audio-driven upper-body animation. We introduce two key methods: Parts-Aware Re-weighting (PAR) and Parts Consistency Enhancement (PCE). PAR dynamically adjusts regional training loss weights based on pose confidence scores, effectively improving visual quality. PCE constructs and trains diffusion-based regional audio-visual classifiers to improve the consistency of motion and co-speech audio. Afterwards, we design two novel inference guidance methods for the foregoing classifiers, Sequential Guidance (SG) and Differential Guidance (DG), to balance efficiency and quality respectively. Additionally, we build CNAS, the first public Chinese News Anchor Speech dataset, to advance research and validation in this field. Extensive experimental results and user studies demonstrate that PAHA significantly outperforms existing methods in audio-motion alignment and video-related evaluations. The codes and CNAS dataset will be released upon acceptance.

  • 5 authors
·
May 6, 2025

SilVar-Med: A Speech-Driven Visual Language Model for Explainable Abnormality Detection in Medical Imaging

Medical Visual Language Models have shown great potential in various healthcare applications, including medical image captioning and diagnostic assistance. However, most existing models rely on text-based instructions, limiting their usability in real-world clinical environments especially in scenarios such as surgery, text-based interaction is often impractical for physicians. In addition, current medical image analysis models typically lack comprehensive reasoning behind their predictions, which reduces their reliability for clinical decision-making. Given that medical diagnosis errors can have life-changing consequences, there is a critical need for interpretable and rational medical assistance. To address these challenges, we introduce an end-to-end speech-driven medical VLM, SilVar-Med, a multimodal medical image assistant that integrates speech interaction with VLMs, pioneering the task of voice-based communication for medical image analysis. In addition, we focus on the interpretation of the reasoning behind each prediction of medical abnormalities with a proposed reasoning dataset. Through extensive experiments, we demonstrate a proof-of-concept study for reasoning-driven medical image interpretation with end-to-end speech interaction. We believe this work will advance the field of medical AI by fostering more transparent, interactive, and clinically viable diagnostic support systems. Our code and dataset are publicly available at SiVar-Med.

  • 6 authors
·
Apr 14, 2025 2

Interactive Segmentation Model for Placenta Segmentation from 3D Ultrasound images

Placenta volume measurement from 3D ultrasound images is critical for predicting pregnancy outcomes, and manual annotation is the gold standard. However, such manual annotation is expensive and time-consuming. Automated segmentation algorithms can often successfully segment the placenta, but these methods may not consistently produce robust segmentations suitable for practical use. Recently, inspired by the Segment Anything Model (SAM), deep learning-based interactive segmentation models have been widely applied in the medical imaging domain. These models produce a segmentation from visual prompts provided to indicate the target region, which may offer a feasible solution for practical use. However, none of these models are specifically designed for interactively segmenting 3D ultrasound images, which remain challenging due to the inherent noise of this modality. In this paper, we evaluate publicly available state-of-the-art 3D interactive segmentation models in contrast to a human-in-the-loop approach for the placenta segmentation task. The Dice score, normalized surface Dice, averaged symmetric surface distance, and 95-percent Hausdorff distance are used as evaluation metrics. We consider a Dice score of 0.95 a successful segmentation. Our results indicate that the human-in-the-loop segmentation model reaches this standard. Moreover, we assess the efficiency of the human-in-the-loop model as a function of the amount of prompts. Our results demonstrate that the human-in-the-loop model is both effective and efficient for interactive placenta segmentation. The code is available at https://github.com/MedICL-VU/PRISM-placenta.

  • 9 authors
·
Jul 10, 2024

Wav2Small: Distilling Wav2Vec2 to 72K parameters for Low-Resource Speech emotion recognition

Speech Emotion Recognition (SER) needs high computational resources to overcome the challenge of substantial annotator disagreement. Today SER is shifting towards dimensional annotations of arousal, dominance, and valence (A/D/V). Universal metrics as the L2 distance prove unsuitable for evaluating A/D/V accuracy due to non converging consensus of annotator opinions. However, Concordance Correlation Coefficient (CCC) arose as an alternative metric for A/D/V where a model's output is evaluated to match a whole dataset's CCC rather than L2 distances of individual audios. Recent studies have shown that Wav2Vec2.0 / WavLM architectures outputing a float value for each A/D/V dimension achieve today's State-of-the-art (SOTA) CCC on A/D/V. The Wav2Vec2.0 / WavLM family has high computational footprint, but training tiny models using human annotations has been unsuccessful. In this paper we use a large Transformer SOTA A/D/V model as Teacher/Annotator to train 5 student models: 4 MobileNets and our proposed Wav2Small, using only the Teacher's A/D/V predictions instead of human annotations. We chose MobileNet-V4 / MobileNet-V3 as students, as MobileNet has been designed for fast execution times. We propose Wav2Small an architecture designed for minimal parameter number and RAM consumption. Wav2Small with an .onnx (quantized) of only 60KB is a potential solution for A/D/V on hearing aids, having only 72K parameters vs 3.12M parameters for MobileNet-V4-Small. The Teacher model we construct sets a new SOTA on the MSP Podcast Test-1 dataset with valence CCC=0.676.

  • 7 authors
·
Aug 25, 2024

Heart Failure Prediction using Modal Decomposition and Masked Autoencoders for Scarce Echocardiography Databases

Heart diseases remain the leading cause of mortality worldwide, implying approximately 18 million deaths according to the WHO. In particular, heart failures (HF) press the healthcare industry to develop systems for their early, rapid, and effective prediction. This work presents an automatic system based on a novel framework which combines Modal Decomposition and Masked Autoencoders (MAE) to extend the application from heart disease classification to the more challenging and specific task of heart failure time prediction, not previously addressed to the best of authors' knowledge. This system comprises two stages. The first one transforms the data from a database of echocardiography video sequences into a large collection of annotated images compatible with the training phase of machine learning-based frameworks and deep learning-based ones. This stage includes the use of the Higher Order Dynamic Mode Decomposition (HODMD) algorithm for both data augmentation and feature extraction. The second stage builds and trains a Vision Transformer (ViT). MAEs based on a combined scheme of self-supervised (SSL) and supervised learning, so far barely explored in the literature about heart failure prediction, are adopted to effectively train the ViT from scratch, even with scarce databases. The designed neural network analyses in real-time images from echocardiography sequences to estimate the time of happening a heart failure. This approach demonstrates to improve prediction accuracy from scarce databases and to be superior to several established ViT and Convolutional Neural Network (CNN) architectures. The source code will be incorporated into the next version release of the ModelFLOWs-app software (https://github.com/modelflows/ModelFLOWs-app).

  • 5 authors
·
Apr 10, 2025

Headset: Human emotion awareness under partial occlusions multimodal dataset

The volumetric representation of human interactions is one of the fundamental domains in the development of immersive media productions and telecommunication applications. Particularly in the context of the rapid advancement of Extended Reality (XR) applications, this volumetric data has proven to be an essential technology for future XR elaboration. In this work, we present a new multimodal database to help advance the development of immersive technologies. Our proposed database provides ethically compliant and diverse volumetric data, in particular 27 participants displaying posed facial expressions and subtle body movements while speaking, plus 11 participants wearing head-mounted displays (HMDs). The recording system consists of a volumetric capture (VoCap) studio, including 31 synchronized modules with 62 RGB cameras and 31 depth cameras. In addition to textured meshes, point clouds, and multi-view RGB-D data, we use one Lytro Illum camera for providing light field (LF) data simultaneously. Finally, we also provide an evaluation of our dataset employment with regard to the tasks of facial expression classification, HMDs removal, and point cloud reconstruction. The dataset can be helpful in the evaluation and performance testing of various XR algorithms, including but not limited to facial expression recognition and reconstruction, facial reenactment, and volumetric video. HEADSET and its all associated raw data and license agreement will be publicly available for research purposes.

  • 5 authors
·
Feb 14, 2024

Language-guided Open-world Video Anomaly Detection

Video anomaly detection models aim to detect anomalies that deviate from what is expected. In open-world scenarios, the expected events may change as requirements change. For example, not wearing a mask is considered abnormal during a flu outbreak but normal otherwise. However, existing methods assume that the definition of anomalies is invariable, and thus are not applicable to the open world. To address this, we propose a novel open-world VAD paradigm with variable definitions, allowing guided detection through user-provided natural language at inference time. This paradigm necessitates establishing a robust mapping from video and textual definition to anomaly score. Therefore, we propose LaGoVAD (Language-guided Open-world VAD), a model that dynamically adapts anomaly definitions through two regularization strategies: diversifying the relative durations of anomalies via dynamic video synthesis, and enhancing feature robustness through contrastive learning with negative mining. Training such adaptable models requires diverse anomaly definitions, but existing datasets typically provide given labels without semantic descriptions. To bridge this gap, we collect PreVAD (Pre-training Video Anomaly Dataset), the largest and most diverse video anomaly dataset to date, featuring 35,279 annotated videos with multi-level category labels and descriptions that explicitly define anomalies. Zero-shot experiments on seven datasets demonstrate SOTA performance. Data and code will be released.

  • 5 authors
·
Mar 17, 2025

From Clinical Intent to Clinical Model: An Autonomous Coding-Agent Framework for Clinician-driven AI Development

Clinical AI development has traditionally followed a collaborative paradigm that depends on close interaction between clinicians and specialized AI teams. This paradigm imposes a practical challenge: clinicians must repeatedly communicate and refine their requirements with AI developers before those requirements can be translated into executable model development. This iterative process is time-consuming, and even after repeated discussion, misalignment may still exist because the two sides do not fully share each other's expertise. However, autonomous coding agents may change this paradigm, raising the possibility that clinicians could develop clinical AI models independently through natural-language interaction alone. In this study, we present such an autonomous prototype for clinician-driven clinical AI development. We evaluated the system on five clinical tasks spanning dermoscopic lesion classification, melanoma-versus-nevus triage, wrist-fracture detection (including a weakly supervised variant with only 5% bounding-box annotations), and debiased pneumothorax classification on chest radiographs. Across these settings, the system consistently developed models from clinician requests and achieved promising performance. Notably, in a debiased pneumothorax classification task on chest radiographs, where chest drains can act as a major confounder, the system successfully mitigated shortcut learning and nearly halved the model's reliance on chest drains. These findings provide proof of concept that autonomous coding agents may help shift clinical AI development toward a more clinician-driven paradigm, reducing the communication overhead and dependence on specialized AI developers. Although further validation and robustness assessment are needed, this study suggests a promising path toward making clinical AI development more accessible.

  • 6 authors
·
Apr 17

PeopleSansPeople: A Synthetic Data Generator for Human-Centric Computer Vision

In recent years, person detection and human pose estimation have made great strides, helped by large-scale labeled datasets. However, these datasets had no guarantees or analysis of human activities, poses, or context diversity. Additionally, privacy, legal, safety, and ethical concerns may limit the ability to collect more human data. An emerging alternative to real-world data that alleviates some of these issues is synthetic data. However, creation of synthetic data generators is incredibly challenging and prevents researchers from exploring their usefulness. Therefore, we release a human-centric synthetic data generator PeopleSansPeople which contains simulation-ready 3D human assets, a parameterized lighting and camera system, and generates 2D and 3D bounding box, instance and semantic segmentation, and COCO pose labels. Using PeopleSansPeople, we performed benchmark synthetic data training using a Detectron2 Keypoint R-CNN variant [1]. We found that pre-training a network using synthetic data and fine-tuning on various sizes of real-world data resulted in a keypoint AP increase of +38.03 (44.43 pm 0.17 vs. 6.40) for few-shot transfer (limited subsets of COCO-person train [2]), and an increase of +1.47 (63.47 pm 0.19 vs. 62.00) for abundant real data regimes, outperforming models trained with the same real data alone. We also found that our models outperformed those pre-trained with ImageNet with a keypoint AP increase of +22.53 (44.43 pm 0.17 vs. 21.90) for few-shot transfer and +1.07 (63.47 pm 0.19 vs. 62.40) for abundant real data regimes. This freely-available data generator should enable a wide range of research into the emerging field of simulation to real transfer learning in the critical area of human-centric computer vision.

  • 9 authors
·
Dec 16, 2021

Towards a Single Unified Model for Effective Detection, Segmentation, and Diagnosis of Eight Major Cancers Using a Large Collection of CT Scans

Human readers or radiologists routinely perform full-body multi-organ multi-disease detection and diagnosis in clinical practice, while most medical AI systems are built to focus on single organs with a narrow list of a few diseases. This might severely limit AI's clinical adoption. A certain number of AI models need to be assembled non-trivially to match the diagnostic process of a human reading a CT scan. In this paper, we construct a Unified Tumor Transformer (UniT) model to detect (tumor existence and location) and diagnose (tumor characteristics) eight major cancer-prevalent organs in CT scans. UniT is a query-based Mask Transformer model with the output of multi-organ and multi-tumor semantic segmentation. We decouple the object queries into organ queries, detection queries and diagnosis queries, and further establish hierarchical relationships among the three groups. This clinically-inspired architecture effectively assists inter- and intra-organ representation learning of tumors and facilitates the resolution of these complex, anatomically related multi-organ cancer image reading tasks. UniT is trained end-to-end using a curated large-scale CT images of 10,042 patients including eight major types of cancers and occurring non-cancer tumors (all are pathology-confirmed with 3D tumor masks annotated by radiologists). On the test set of 631 patients, UniT has demonstrated strong performance under a set of clinically relevant evaluation metrics, substantially outperforming both multi-organ segmentation methods and an assembly of eight single-organ expert models in tumor detection, segmentation, and diagnosis. Such a unified multi-cancer image reading model (UniT) can significantly reduce the number of false positives produced by combined multi-system models. This moves one step closer towards a universal high-performance cancer screening tool.

  • 25 authors
·
Jan 28, 2023

Expert-level vision-language foundation model for real-world radiology and comprehensive evaluation

Radiology is a vital and complex component of modern clinical workflow and covers many tasks. Recently, vision-language (VL) foundation models in medicine have shown potential in processing multimodal information, offering a unified solution for various radiology tasks. However, existing studies either pre-trained VL models on natural data or did not fully integrate vision-language architecture and pretraining, often neglecting the unique multimodal complexity in radiology images and their textual contexts. Additionally, their practical applicability in real-world scenarios remains underexplored. Here, we present RadFound, a large and open-source vision-language foundation model tailored for radiology, that is trained on the most extensive dataset of over 8.1 million images and 250,000 image-text pairs, covering 19 major organ systems and 10 imaging modalities. To establish expert-level multimodal perception and generation capabilities, RadFound introduces an enhanced vision encoder to capture intra-image local features and inter-image contextual information, and a unified cross-modal learning design tailored to radiology. To fully assess the models' capability, we construct a benchmark, RadVLBench, including radiology interpretation tasks like medical vision-language question-answering, as well as text generation tasks ranging from captioning to report generation. We also propose a human evaluation framework. When evaluated on the real-world benchmark involving three representative modalities, 2D images (chest X-rays), multi-view images (mammograms), and 3D images (thyroid CT scans), RadFound significantly outperforms other VL foundation models on both quantitative metrics and human evaluation. In summary, the development of RadFound represents an advancement in radiology generalists, demonstrating broad applicability potential for integration into clinical workflows.

  • 9 authors
·
Sep 24, 2024