PMCID string | Title string | FullText string |
|---|---|---|
PMC11075828 | Direct and indirect effects of CYTOR lncRNA regulate HIV gene expression | The implementation of antiretroviral therapy (ART) has effectively restricted the transmission of Human Immunodeficiency Virus (HIV) and improved overall clinical outcomes. However, a complete cure for HIV remains out of reach, as the virus persists in a stable pool of infected cell reservoir that is resistant to thera... |
PMC12118871 | PCYT2 overexpression induces mitochondrial damage and promotes apoptosis in hepatocellular carcinoma cells | Phosphatidylethanolamine cytidyltransferase 2 (PCYT2) is commonly regarded as the rate-limiting enzyme in eukaryotic phosphatidylethanolamine synthesis. However, the role of PCYT2 in the development of hepatocellular carcinoma (HCC) unknow. In this study, the role of PCYT2 overexpression in the development of HCC was e... |
PMC1462997 | Derivation of normal macrophages from human embryonic stem (hES) cells for applications in HIV gene therapy | Many novel studies and therapies are possible with the use of human embryonic stem cells (hES cells) and their differentiated cell progeny. The hES cell derived CD34 hematopoietic stem cells can be potentially used for many gene therapy applications. Here we evaluated the capacity of hES cell derived CD34 cells to give... |
PMC1160574 | Derivation of Multipotent Mesenchymal Precursors from Human Embryonic Stem Cells | Human embryonic stem cells provide access to the earliest stages of human development and may serve as a source of specialized cells for regenerative medicine. Thus, it becomes crucial to develop protocols for the directed differentiation of embryonic stem cells into tissue-restricted precursors. Here, we present cultu... |
PMC12396968 | Multimodal profiling reveals tissue-directed signatures of human immune cells altered with age | "The immune system comprises multiple cell lineages and subsets maintained in tissues throughout the(...TRUNCATED) |
PMC12435838 | Organ-specific features of human kidney lymphatics are disrupted in chronic transplant rejection | "Lymphatic vessels maintain tissue fluid homeostasis and modulate inflammation, yet their spatial or(...TRUNCATED) |
PMC11578878 | An integrated transcriptomic cell atlas of human neural organoids | "Human neural organoids, generated from pluripotent stem cells in vitro, are useful tools to study h(...TRUNCATED) |
PMC12595314 | "Establishment and comprehensive characterization of a subline with highly bone-metastatic propensit(...TRUNCATED) | "Lung cancer remains a leading cause of cancer-related mortality worldwide , with bone metastases re(...TRUNCATED) |
PMC8809252 | Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches | "The liver is the largest solid organ in the body, yet it remains incompletely characterized. Here w(...TRUNCATED) |
PMC11699618 | Bivalent SMAC mimetic APG-1387 reduces HIV reservoirs and limits viral rebound in humanized mice | "Latent viral reservoirs (VRs) represent a main barrier to HIV cure. Thus, developing new approaches(...TRUNCATED) |
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