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ec34e9b7-1155-47a8-bd52-eda40d243e59
reasoning
medical
disease_knowledge
easy
pubmed_classified
Do [ Larger heads compensate for an increased risk of THA dislocation in high-risk patients ]?
yes Our results with 40 and 44 mm heads and the existing literature confirm much higher joint stability and, thus, significantly reduced dislocation risk with larger prosthetic heads in THA. Their use is, therefore, justified in high-risk patients and should be considered in future THA.
true
open_ended
en
train
medical_disease_knowledge_easy
0a48a3e5-0b02-46ab-b6f0-ce176f7b86bf
qa
medical
clinical_qa
hard
icliniq
Hello doctor,I have got pretty bad eczema. I have been using Doublebase gel that my GP gave me, but does not seem to be working. What is annoying is that I have noticed very deep wrinkles under my eyes where my skin is mostly dry. Could I get rid of these? I am only 18 and I cannot even look in the mirror or smile beca...
Hi, Welcome to Chat Doctor forum. I have read your query in detail and do understand your concern (attachment removed to protect patient identity). 1. You seem to be suffering from atopic dermatitis.2. The wrinkles you are referring to could be actually Dennie-Morgan folds (folds below the lower eyelid as a result of e...
true
open_ended
en
train
medical_clinical_qa_hard
2a913ef9-863c-4693-917c-2e5a08ff7551
drug_information
medical
drug_information
hard
healthcaremagic
My son has been a chronic asthmatic for 17 years, since age 1 and has allergies as well. He has always managed with daily dosages of his inhaler and is now on Advair. However, the past few times that he has been checked the doctor said that he has no asthma symptoms; at the time the doctor checked him he was not feelin...
Hie, i am a patient of same thing,I have been a patient OGF seasonal bronchitis since the time I was 5 years of age,now I am 21.however since last 1.5 years,I have developed signs of permanent asthma, i should rather consider it as peculiar asthma, i am normal most of the time by taking a tablet of MONTE LC(MONTELUKAST...
true
open_ended
en
train
medical_drug_information_hard
2731b9d2-878a-44b6-b28f-199e3fb2f5fa
qa
medical
clinical_qa
medium
icliniq
Hi doctor,I went to the allergist a week back and he said my nasal passages were swollen up. He prescribed QNASL. I am going to meet an ENT doctor in a day or so. I cannot breathe well or smell. What can an ENT doctor do for me?
Hi. The steroid nasal spray you are using has local steroid which helps in reducing the swelling. This spray you will have to use for around six weeks. Secondly, to treat nose block you may use local decongestant nose ChatDoctor. If you have excessive sneezing you should use antihistamines also. If your problem is chro...
true
open_ended
en
train
medical_clinical_qa_medium
990c7e2d-c3c3-475e-b715-017b00c1f25e
qa
medical
clinical_qa
medium
icliniq
Hello doctor,I am 32 years old. I was using self-tanning creams around seven years all year long. I have stopped for the last two years. I am worried because I have read that self-tanning creams are causing cancer and tumors. Is it true? Are they out of my system or will it take years to appear if they caused me cancer...
Hello, Welcome to Chat Doctor forum. Yes, self-tanning lotions are known to cause skin cancer. Please stop using it and avoid exposure to sunlight without a sunscreen. Use a sunscreen with SPF 50 or more, apply every fourth hourly. Look for any changes in the skin, any bumps that look different, any changes in moles. S...
true
open_ended
en
train
medical_clinical_qa_medium
4dfc150c-c387-427b-b559-058dca05d7c0
treatment_overview
medical
treatment_overview
hard
healthcaremagic
I had a UA that was positive for bilirubin and leukocyte esterase. Also had red and white blood cells, epithelial cells, bacteria and mucus. Free hemoglobin was also detected.Was surgically treated for left ureterovesical reflux and periureteral diverticulum, and a right ectopic ureter. This was in 1996 when I was 8. I...
Good Day! Leukocyte esterase, RBC, and WBC may indicate a urinary tract infection. I would suggest doing a Urine culture since it is the most accurate examination to check confirm an infection, and it also identifies the bacteria and tells us what antibiotics are appropriate to treat the infection. With the bulge on th...
true
open_ended
en
train
medical_treatment_overview_hard
c7dd9115-e152-418c-940f-c466aee8e47c
qa
medical
drug_information
easy
medquad_nih
Who is at risk for Overweight and Obesity? ?
Overweight and obesity affect Americans of all ages, sexes, and racial/ethnic groups. This serious health problem has been growing over the last 30 years. Adults According to the National Health and Nutrition Examination Survey (NHANES) 20092010, almost 70 percent of Americans are overweight or obese. The survey also s...
true
open_ended
en
train
medical_drug_information_easy
86f97272-9170-4e5f-90b5-24366a05fba9
reasoning
medical
disease_knowledge
easy
pubmed_classified
Does impairment of executive function and attention predict onset of affective disorder in healthy high-risk twins?
yes Among healthy individuals at heritable risk for affective disorder, discrete cognitive deficits, especially within executive function and attention, seem to predict subsequent onset of affective illness.
true
open_ended
en
train
medical_disease_knowledge_easy
26ccae1b-a0d8-4ac9-847d-fa646dc4af4b
explanation
medical
medical_explanation
easy
medquad_nih
What is (are) Gamma aminobutyric acid transaminase deficiency ?
GABA (gamma-aminobutyric acid) is an important molecule which slows down the activity of cells in the brain.[1] GABA is broken down in the body by a substance known as 4-aminobutyrate aminotransferase, also known as GABA-transaminase or GABA-T.[1] Mutations in the ABAT gene can cause less GABA-T to be made, a condition...
true
open_ended
en
train
medical_medical_explanation_easy
635c143e-516c-476d-9913-69021ed5a053
qa
medical
clinical_qa
easy
icliniq
Hello doctor,Can I take Testosterone cypionate and Trenbolone enanthate, while on high blood pressure medication Benicar 20 mg?
Hello. If you have low testosterone and have been given a prescription for using testosterone, after consulting an endocrinologist you can take it. But always remember you should not have very high doses of testosterone since hypertension already puts the cardiac system under some risk for development of coronary arter...
true
open_ended
en
train
medical_clinical_qa_easy
3f0fc845-8084-43cb-a606-e4782da9e968
reasoning
medical
symptom_reasoning
easy
pubmed_classified
Is increased fibronectin expression in developing embryos associated with abnormal notochord in the Adriamycin rat model?
yes Adriamycin-induced increased expression of FN, in the ARM, may contribute to abnormal notochord development leading to the VACTERL association.
true
open_ended
en
train
medical_symptom_reasoning_easy
c5dc896b-45c4-4cc2-8992-64696d37be6f
drug_information
medical
drug_information
hard
healthcaremagic
Hi doctor, I m 30 yr old. I having pcod and get treatment for 3 months i got conceived but it miscarriage in 37 days.after I didn t take any medication and got regular periods after 6 months again i conceived and miscarriage in 40 days. next month i got periods after that I didn t get periods. i went to the doctor , th...
Hello, Go for Ayurveda treatment, you will get conceive. There are many medicines which help you. POD (Polycystic ovary disease), is normal for unmarried women, and it is not complicated. It never affects pregnancy. If you believe consult any good ayurvedic doctor for better treatment. Or call me 8818805637, or meet me...
true
open_ended
en
train
medical_drug_information_hard
fc381d59-13cf-468c-805f-e52f48d5f6b7
reasoning
medical
disease_knowledge
easy
pubmed_classified
Do control of a Robotic Hand Using a Tongue Control System-A Prosthesis Application?
yes The findings indicate that using the ITCS control scheme could allow for faster activation of specific grasps or functions compared with a conventional EMG control scheme.
true
open_ended
en
train
medical_disease_knowledge_easy
7a3d141b-0fa1-49e3-aa7e-3aea9ef252f0
treatment_overview
medical
treatment_overview
medium
healthcaremagic
I was told I had a hernia because my naval kept bleeding where I had to place a pad on it.. I just had Gall Bladder surgery and the doctor when through my naval instead of another spot. I was told that I will bleed every month when I get my menstruation and there is nothing that can be done. I have pain and a very foul...
Hi.it is best if you have it checked by a general surgeon for clinical evaluation. Was it laparoscopic cholecystectomy that was done to you? There are incidents wherein post-surgery, these things happen in the previous naval port area of the patient. Also, doctors evaluation is needed to rule-out racial cyst problems w...
true
open_ended
en
train
medical_treatment_overview_medium
bb894d73-0015-4a73-ab47-6a65229b21c0
reasoning
medical
disease_knowledge
easy
pubmed_classified
Are joint destruction after glucocorticoids withdrawn in early rheumatoid arthritis . Arthritis and Rheumatism Council Low Dose Glucocorticoid Study Group?
yes Joint destruction resumed after discontinuation of prednisolone. This corroborates the previously reported therapeutic effect and challenges current concepts of disease pathogenesis.
true
open_ended
en
train
medical_disease_knowledge_easy
f500a6dd-034c-49b4-bc26-3d76c5e90b94
explanation
medical
medical_explanation
easy
medquad_nih
What is (are) Short Bowel Syndrome ?
Short bowel syndrome is a group of problems related to poor absorption of nutrients. Short bowel syndrome typically occurs in people who have - had at least half of their small intestine removed and sometimes all or part of their large intestine removed - significant damage of the small intestine - poor motility, or mo...
true
open_ended
en
train
medical_medical_explanation_easy
d64754b6-f437-4dbb-a29f-c3855cd6069d
reasoning
medical
symptom_reasoning
easy
pubmed_classified
Is essential role of aldehyde dehydrogenase 1A3 for the maintenance of non-small cell lung cancer stem cells associated with the STAT3 pathway?
yes Our data show that ALDH1A3 is the predominant ALDH isozyme responsible for ALDH activity and tumorigenicity in most NSCLCs, and that inhibiting either ALDH1A3 or the STAT3 pathway are potential therapeutic strategies to eliminate the ALDH(+) subpopulation in NSCLCs.
true
open_ended
en
train
medical_symptom_reasoning_easy
5e412913-d9fd-4966-8af2-d79ac549cb45
treatment_overview
medical
treatment_overview
medium
healthcaremagic
I HAVE AN ENLARGED PROSTATE......PROBLEMS WITH URINATION...ALSO HAVE PAIN AND DICOMFORT IN THE PENIS....VERY SENSITIVE IN THE TIP OF PENIS....COULD THIS BE CAUSE BY AN ENLARGED PROSTATE/....AND WHAT WOULD BE A GOOD TREATMENT FOR THIS????.....i am 56 years old....5 ft 9 and weigh about 190 pounds....i good health otherw...
Hi. I would first like to know why your prostate is enlarged as per your doctor. Is it inflammation or prostatitis or BPH-Benign hyperplasia of prostate? If it is the first one then pain and burning can happen. You should get your urine culture and Semen culture done to rule out any infection which can be treated with ...
true
open_ended
en
train
medical_treatment_overview_medium
e74a1c06-ec31-40b6-8e86-9df684f6d466
reasoning
medical
disease_knowledge
easy
pubmed_classified
Are polymorphisms in the telomerase reverse transcriptase promoter associated with risk of breast cancer : A meta-analysis?
yes This meta-analysis suggested that TERT rs2736109, rs2853669, rs2736098, and rs10069690 polymorphisms were associated with increased risk of developing breast cancer.
true
open_ended
en
train
medical_disease_knowledge_easy
db9c928e-fb1e-4e10-a4f2-dababedf7c13
qa
medical
clinical_qa
hard
icliniq
Hello Doctor,My mother was operated on 18th July for cervical cancer (Wertheim\\s Hysterectomy).The operation was successful and she is fine and recovering.After the surgical biopsy, they declared it as stage 2B.Further we sent her slides to the laboratory for review and there they found the left parametrium free and r...
Hello. I went through the reports and my opinion is as follows
true
open_ended
en
train
medical_clinical_qa_hard
51cd93b4-0b11-48ba-b1c0-b0a63455b408
explanation
medical
medical_explanation
easy
medquad_nih
What is (are) Proximal symphalangism ?
Proximal symphalangism, which is also called Cushing's symphalangism, is a rare genetic condition characterized by the fusion of the proximal joints in the hands and feet. These individuals usually have straight fingers and are unable to make a fist. Other joints may also be affected, leading to stiff joints in the elb...
true
open_ended
en
train
medical_medical_explanation_easy
d4a0f14e-55d2-4b07-936d-982261a7349c
treatment_overview
medical
treatment_overview
medium
healthcaremagic
Sir, my wife is suffering from amoebic liver abscess. Allopathy doctors recommend for aspiration using catheter.Though needle aspiration has been done once Is there any alternative treatment like ayurvedic which may absorb pus in the liver and thus avoiding aspiration
Hello, Sorry to hear about your wives illness. An amoebic liver abscess can completely recover using antibiotics like metronidazole.However if the abscess is very large or close to the surface of the liver then medicines should be combined with aspiration as there chances of rupture of the abscess. Aspiration is also i...
true
open_ended
en
train
medical_treatment_overview_medium
4edd335a-9804-459c-a40d-1b58f88c0e4d
reasoning
medical
medical_explanation
easy
medquad_nih
How many people are affected by citrullinemia ?
Type I citrullinemia is the most common form of the disorder, affecting about 1 in 57,000 people worldwide. Type II citrullinemia is found primarily in the Japanese population, where it occurs in an estimated 1 in 100,000 to 230,000 individuals. Type II also has been reported in other populations, including people from...
true
open_ended
en
train
medical_medical_explanation_easy
15b2a338-f9f1-4d1d-b00f-7abdcf994b63
drug_information
medical
drug_information
medium
healthcaremagic
I have a pain in my left arm along with cold chills after urinating which leads me to go to the doctor for a UTI. It is always positive. The pain and cold chills stop after I take a few antibiotics that the doctor has subscribed. Why the pain in the arm?
Hi, As mentioned by you about the UTI, I will recommend to first strengthen the core and the pelvic floor, as the muscles of the core and pelvic floor will help the bladder to get completely empty and avoid any backlog Chat Doctor. Also, now looking to the pain in the left arm, it is needed to understand by taking a ne...
true
open_ended
en
train
medical_drug_information_medium
1e849a13-7f62-44d9-a015-6f537f67e59b
explanation
medical
drug_information
easy
medquad_nih
What are the complications of Lupus Nephritis ?
In many cases, treatment is effective in completely or partially controlling lupus nephritis, resulting in few, if any, further complications. However, even with treatment, 10 to 30 percent of people with lupus nephritis develop kidney failure, described as end-stage renal disease when treated with blood-filtering trea...
true
open_ended
en
train
medical_drug_information_easy
33b68618-8ed0-434b-9e11-281258ec0db6
treatment_overview
medical
treatment_overview
hard
healthcaremagic
I have allergies and asthma. I also have high blood pressure. All of these symptoms are being treated and normally fairly control. I now have a sinus infection and so my pulmonologist prescribed Zpack and Claritin D until the congestion gets better. I am on the 3rd day of the Zpack. I have a fever and am now experienci...
Hello dear thanks for your query at ChatDoctoryour consultant had prescribed Pack that contains azithromycin, its antibiotic used in upper respiratory tract infection.it will take at least two to three days for antibiotic response to come and control the infection. High pulse rate and fever indicate that infection stil...
true
open_ended
en
train
medical_treatment_overview_hard
897ba2ad-cd09-4d19-bbc0-a167d86c954e
reasoning
medical
disease_knowledge
easy
pubmed_classified
Are allergic rhinitis and allergy risk factors for otitis media with effusion : A meta-analysis?
yes Allergic rhinitis and allergy appear to be risk factors for otitis media with effusion.
true
open_ended
en
train
medical_disease_knowledge_easy
4e02917d-b5eb-4dfc-9132-98c0cf90c680
qa
medical
clinical_qa
medium
icliniq
Hello doctor,I am being treated for chronic prostatitis rebounce. It is now the third day I am taking Tavanik (Levofloxacin) 500 mg a day. I am taking it the same time each day among other medications. One of them is Vigantol 1000 I.E. My doctor told me to take Tavanik at least one hour after and before other medicatio...
Hi, Welcome to Chat Doctor forum. I have gone through your query, your doctor had suggested you take Levofloxacin before any other medication as the absorption will be better. Usually, we instruct patients to wait for an hour at least so that the ChatDoctor. Unless you took both the medication together, even if you had...
true
open_ended
en
train
medical_clinical_qa_medium
6c00075b-cfce-4137-a4e2-2c018779efc0
qa
medical
clinical_qa
hard
icliniq
over the past 20 hours ive had constant lightheadedness/vertigo, and during the day today ive gradually started feeling nauseous (no vomiting), abdominal pain/cramping, headache, neck stiffness. in the past week ive had some abdominal pain on/off and acid reflux, as well as headaches and general soreness in my neck and...
hi, thanks for your query the temporal profile suggests mild ongoing inflammation, that is causing the problem. it could be subclinical inflammation and or infection like a stomach bug. also a possibility of ChatDoctor. to amphe along with a
true
open_ended
en
train
medical_clinical_qa_hard
48350144-5122-40f2-8fa5-fae3e8605634
treatment_overview
medical
treatment_overview
medium
healthcaremagic
I want to recover from porn viewing addiction, Male, 29, I have been unable to stop for 8 years now, at the most 2-3 months I could abstain, but then I tend to relapse back into the habit. I m married since past 4 years and so want to recover fast. I have note taken any help so far, could you suggest me what to do and ...
HIT hanks for using Chat Doctor It is a very common disorder these days. You should consult a psychiatrist and psychologist for proper management. You can take some antidepressant that would help to control anxiety and thoughts about watching porn stuff. Psychotherapy would help to control these thoughts by thoughts' s...
true
open_ended
en
train
medical_treatment_overview_medium
1225c244-8145-4601-aefe-e46b5f8707c0
qa
medical
clinical_qa
medium
icliniq
Hello doctor, I am having cervical fusion 3 levels 5/17. I am on 8 mg of Suboxone daily. I told the surgeon that I do not want opioids. Can I stay on 8 mg up to the surgery morning? I do not want to stop and have withdrawals or take any opioids before or after the procedure.
Hi, Welcome to Chat Doctor forum.. Suboxone (Buprenorphine) is given to treat opioid dependence. Prozac is an antidepressant. I think because of your disease process, cervical radiculopathy in your case, you have been taking some pain killers mostly opioids for a long time. Doctor might have prescribed Suboxone to take...
true
open_ended
en
train
medical_clinical_qa_medium
0948f514-e95b-4ddf-b5e1-2973c9dfb95b
reasoning
medical
symptom_reasoning
easy
pubmed_classified
Does early maternal anxiety predict cognitive and behavioural outcomes of VLBW children at 24 months corrected age?
yes These results suggest that early intervention programmes targeting anxious mothers of VLBW infants are indicated, to promote optimal developmental outcomes.
true
open_ended
en
train
medical_symptom_reasoning_easy
a579d752-05f4-4f88-8451-1526828c3eb6
explanation
medical
treatment_overview
easy
medquad_nih
What are the treatments for Buschke Ollendorff syndrome ?
How might Buschke Ollendorff syndrome be treated? There is currently no cure for BOS. Surgical removal of lesions on or under the skin may be done for cosmetic purposes. In some patients, surgical treatment of deafness may be possible. Surgery might also be necessary for some of the signs or symptoms associated with BO...
true
open_ended
en
train
medical_treatment_overview_easy
f713d186-c23b-41ed-90ac-5ba1c5d1de0d
drug_information
medical
drug_information
hard
healthcaremagic
i had the helicobacter pylori infection took a series of antibotics and do not feel any better. have had diaerhia for 2 months. bad stomach pains, pain under breast bone, right side and back and like gurgling in stomach with burning. i dont have an appointment with the GI doctor until the end of Feb. I just feel so bad...
Dear I can understand your concern. H.pylori infection causes gastritis and gastric ulcer along with duodenal ulcer. Patients have complaints of pain upper stomach associated with nausea, gastric fullness, bloating etc. For H. Pylori treatment we use two antibiotics along with one proton pump inhibitor such as pantopra...
true
open_ended
en
train
medical_drug_information_hard
7f532022-2d06-4079-b2a2-9795c8f21672
reasoning
medical
disease_knowledge
easy
pubmed_classified
Can gas vesicles be detected by ultrasound?
Gas vesicles have been identified as nanoscale reporters for ultrasound.
true
open_ended
en
train
medical_disease_knowledge_easy
becc4ec3-82e4-410e-bca8-6b91dd27397d
qa
medical
clinical_qa
medium
icliniq
Hello doctor,I have lower back pain in the morning and from recently, I cannot bend and I have weak legs and pain in the calves, hips, and hamstrings. I did some X-ray. Can you interpret it?
Hello, Welcome to Chat Doctor forum. I have seen your reports (attachment removed to protect patient identity). Your X-rays indicate changes of spondylitis in the form of disc space reduction and osteophytes. For the symptoms you have, I would recommend an MRI of the lumbar spine with whole spine screening and back str...
true
open_ended
en
train
medical_clinical_qa_medium
16a526c9-495b-43de-9b51-4b715d0ccfa4
explanation
medical
medical_explanation
easy
medquad_nih
What are the genetic changes related to autosomal dominant nocturnal frontal lobe epilepsy ?
Mutations in the CHRNA2, CHRNA4, and CHRNB2 genes can cause ADNFLE. These genes provide instructions for making different parts (subunits) of a larger molecule called a neuronal nicotinic acetylcholine receptor (nAChR). This receptor plays an important role in chemical signaling between nerve cells (neurons) in the bra...
true
open_ended
en
train
medical_medical_explanation_easy
f27cb989-95e3-4ed9-baa2-6c14a79be75d
treatment_overview
medical
treatment_overview
medium
healthcaremagic
I am 30year old women with one child. I m suffering from pain on left heels from the time of child birth(3yrs). I have severe pain when standing after sitting or lying... intensity of pain varies with climate and after walking some distance..plz tel a remedy
Dear patient You are having plantar fasciitis. Its condition commonly seen in middle-aged women and mostly bilateral. There is inflammation of heel bone at attachments of plantar fascia. This leads to pain on weight-bearing and even at rest. You should wear soft heel cushion in your boot or Chap pals. Start tab diclofe...
true
open_ended
en
train
medical_treatment_overview_medium
59102080-1bef-47b3-9a76-f223cfdfb7f9
drug_information
medical
drug_information
medium
healthcaremagic
i want to know that my gyeno has recommended me femilon conterceptive pills but how to take it and after sex or before it and she has also told me to take it after my second day of my periods?and at what time in the whole day?and after taking these tablets how many times we can have sex in a month?
Hi, Felon is a combined oral contraception pill commonly used for prevent an unwanted pregnancy. Take one active pill (with hormones) once daily for 21 days in a row. If you are using a product with 28 tablets, take an inactive pill once daily for 7 days in a row after you have taken the last active pill. If you start ...
true
open_ended
en
train
medical_drug_information_medium
6e199f67-9c6e-4c09-ad3a-8a4b377dc262
qa
medical
clinical_qa
medium
icliniq
Hello doctor,I have a question about gum bleaching. I was just wondering the price range of undergoing this process. My gums cause me no harm whatsoever, by the way, just appearance purposes.
Hello, Welcome to Chat Doctor forum. You are talking about gum bleaching but I feel it is tooth bleaching and you have a problem with the esthetics of teeth. There can be several reasons for esthetics which are mainly due to discoloration due to stains from tea, ChatDoctor.
true
open_ended
en
train
medical_clinical_qa_medium
7037cb85-6f77-4682-ba41-2439a4563329
qa
medical
clinical_qa
medium
icliniq
Hi doctor,My mum has angiosarcoma in the leg. Amputation would be the only option. But she is not a suitable candidate for surgery. Will radiotherapy help in this condition? Please suggest.
Hi. The usual treatment for angiosarcoma is the removal of the cancerous tumor by surgery. However, in those patients who are unfit for surgery, radiotherapy and chemotherapy are alternatives. Radiotherapy involves the use of radiations to dissolve the tumor and chemotherapy involves medicines for the same. Both these ...
true
open_ended
en
train
medical_clinical_qa_medium
31e2b3aa-894d-4a59-805d-90aae8eb74b4
reasoning
medical
symptom_reasoning
easy
pubmed_classified
Does home and workplace built environment support for physical activity?
yes This study offers empirical evidence on BE supports for domain-specific PA. Findings suggest that diverse, attractive, and walkable neighborhoods around workplaces support walking, bicycling, and use of public transit. Public health practitioners, researchers, and worksite leaders could benefit by utilizing worksit...
true
open_ended
en
train
medical_symptom_reasoning_easy
53f0ac1f-544a-4f0e-91cf-e8e9c0361b39
reasoning
medical
disease_knowledge
easy
pubmed_classified
Does hypertonic saline improve cerebral oxygen delivery after head injury and mild hemorrhage in cats?
no After a combination of hemorrhage and traumatic brain injury, neither 10% hydroxyethyl starch nor 3.0% hypertonic saline restored cerebral oxygen delivery. Although neither trauma alone nor hemorrhage alone altered electroencephalographic activity, the combination produced significant decreases in electroencephalogr...
true
open_ended
en
train
medical_disease_knowledge_easy
f35d5fec-ad84-4cc4-a39a-2b240b383a80
reasoning
medical
symptom_reasoning
easy
pubmed_classified
Can PRL3-zumab inhibit PRL3+ cancer cells in vitro and in vivo?
PRL3-zumab specifically inhibits PRL3+ cancer cells in vivo, but not in vitro.
true
open_ended
en
train
medical_symptom_reasoning_easy
88191f7e-0dd0-46f0-bfcb-17f41956495e
treatment_overview
medical
treatment_overview
medium
healthcaremagic
hey so ive had some pain on my bottom right gums,theres a small cut its sort of healing ,it looks greyish. And my front bottom gum got scraped/cut a bit.I just used a new tooth brush,sometimes i brush too hard. Is there a way to speed up the healing or relieve the pain?
Thanks for using Chat Doctor. Read your query. If I were your treating dentists, I would advise you to apply mucosal or denote ointment on the lesion two to three times daily till the symptoms subside. Avoiding spicy food will be useful. Avoid further trauma to the gums and lips while brushing and do not apply too much...
true
open_ended
en
train
medical_treatment_overview_medium
1751249f-f7a6-4f39-9ec2-2a1b6c7e9f88
reasoning
medical
medical_explanation
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medquad_nih
Do you have information about Blood Thinners
Summary : If you have some kinds of heart or blood vessel disease, or if you have poor blood flow to your brain, your doctor may recommend that you take a blood thinner. Blood thinners reduce the risk of heart attack and stroke by reducing the formation of blood clots in your arteries and veins. You may also take a blo...
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Is preoperative sarcopenia a predictor of postoperative pulmonary complications in esophageal cancer following esophagectomy : A retrospective cohort study?
yes The assessment of sarcopenia may be useful to predict the postoperative pulmonary complications following esophagectomy. On the other hand, sarcopenia does not predict cardiac, infectious, and surgical complications or perioperative function.
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Hi doctor,I have oily skin. I have lots of dark spots and acne on my face. Currently, I am using Clincitop gel. My face skin has turned dark where my body color is normal. I have also lost my skin complexion. How should I get rid of this? Please suggest me.
Hi. Please send good quality photographs of your face taken under natural light for more detailed opinion.Revert back with photographs to a dermatologist online
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Hello doctor,My penis is bend towards left. Will it affect my sexual life? Is there any medical treatment for it other than surgery?Is the shock wave therapy effective in Peyronie\\s disease? Will masturbation get the penis more bend?
Hello. The penis is never straight. When it gets erected it is always been in curvature shape for effective intercourse. However, if you feel excess bending of the penis then Peyronie\\s disease should be suspected for which Collagenase clostridium histolyticum can be used. The surgery is a more effective way of treati...
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Does murine norovirus infection cause major disruptions in the murine intestinal microbiota?
no This is the first study to describe the intestinal microbiota following MNV infection and demonstrates that acute or persistent MNV infection is not associated with major disruptions of microbial communities in Swiss Webster and C57BL/6 mice.
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hello my name is Umair and i am livin gin pakistan, i am 29 years old 5 feet 10 inches in height, recently facing hair loss issue and most importan factor that i am suffering form psoriais, my need to ask if there is any thing that i can do as sometimes i m having scaling on my scalp as well, please guide me for any tr...
Hello. Thank you for writing to upscale psoriasis presents as red, scaly patches. Scaling can be thick, adherent and psoriasis involvement of scalp may be associated with increased hair shedding. If I was the treating doctor I would suggest you to use a coal tar+salicylic acid based shampoo, daily or on alternate days....
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Does methodologic issues regarding the use of three observational study design to assess influenza vaccine effectiveness?
yes Demonstration of a high influenza VE using tests with imperfect sensitivity and specificity should provide reassurance that the program has been effective in reducing influenza illnesses, assuming adequate control of confounding factors.
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Does resistance exercise induce a greater irisin response than endurance exercise?
yes Resistance exercise resulted in significantly greater irisin responses compared with endurance exercise alone, and resistance and endurance exercises combined.
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train
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Do tolerogenic dendritic cells inhibit antiphospholipid syndrome derived effector/memory CD4⁺ T cell response to β2GPI?
yes The inherent tolerance induction resistance of activated T cells present during the development of autoimmune diseases has delayed the application of tDC as an alternative therapy. This study highlights the 10/TGF-DC feasibility to induce antigen-specific unresponsiveness in autoreactive T cells generated in patien...
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Do amino acids change liver growth factors gene expression in malnourished rats?
yes Proline or glutamine supplementation in malnourished rats improves total RNA content in the remnant hepatic tissue. Amino acids administration increased HGF gene expression after partial hepatectomy in malnourished rats, with a greater effect of proline than glutamine.
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Yes Doctor, Can ferrous sulphate and folic acid tablets prevent conception?I have discovered that my wife secretely takes these tables. When we married in 1999, she had first degree barenness, which was treated through laproscopy. After conceiving 2 girls in 2003 and 2005 respectively, she has never conceived and yet I...
Hi, Ferrous sulfate & Folic acid tablets are to treat anemia. Folic acid has an effect of preventing certain spinal abnormalities in fetus. Therefore, you can say, your wife is getting ready for next pregnancy! If she did not conceive n last 8 years, I would suggest - * get her checked by an expert Gynecologist. Few in...
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I have been having swollen feet and have had many tests for blockage in legs, but no Dr can find what s wrong. I was checked for gout, high blood pressure, diabetes, and yet no one can find what s wrong. I have a sister who says I should have my heart checked. I take no prescriptions because I am overall health. I am 2...
What is your average blood pressure. See salt restrictions are like to take low salt content, but that doesn't mean you totally stop salt intake! Feet are like small chambers and gravity affects more to accumulate fluid if any retention is there in leg. As your history doesn't suggest any major pathology, get your thyr...
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Does in vitro exposure to carbon dioxide induce oxidative stress in human peritoneal mesothelial cells?
yes Exposure to both CO(2) and helium induces oxidative stress in mesothelial cells. Hypoxia-reoxygenation may play a role in this process.
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train
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medquad_nih
What is (are) Ehlers-Danlos syndrome, vascular type ?
Ehlers-Danlos syndrome (EDS), vascular type is an inherited connective tissue disorder that is caused by defects in a protein called collagen. It is generally considered the most severe form of Ehlers-Danlos syndrome. Common symptoms include thin, translucent skin; easy bruising; characteristic facial appearance; and f...
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explanation
medical
medical_explanation
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medquad_nih
What is (are) Child Sexual Abuse ?
Sexual abuse is one form of child abuse. It includes a wide range of actions between a child and an adult or older child. Often these involve body contact, but not always. Exposing one's genitals to children or pressuring them for sex is sexual abuse. Using a child for pornography is also sexual abuse. Most sexual abus...
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train
medical_medical_explanation_easy
eac2159a-4e74-4ae6-8ea6-89172064e128
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icliniq
Hello doctor,I had simple extraction of my second bottom tooth. It is day six today since I have removed. I was feeling major pain a few days ago but it is fading away day by day. I actually feel no pain in the morning but in the afternoon I feel discomfort. When can all this go away? I was expecting to be healed alrea...
Hi, Welcome to Chat Doctor forum. Yes, you should have been fine till now as advised by your dentist but that was when everything post-extraction would have been fine. Unfortunately, in your case, you have got dislodgement of the blood clot after the exaction was done and this condition is called as ChatDoctor. The pai...
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medical
medical_explanation
easy
medquad_nih
What is (are) Mainzer-Saldino syndrome ?
Mainzer-Saldino syndrome is a disorder characterized by kidney disease, eye problems, and skeletal abnormalities. People with Mainzer-Saldino syndrome have chronic kidney disease that begins in childhood and gets worse over time. The rate at which the kidney disease worsens is variable, but the condition eventually lea...
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train
medical_medical_explanation_easy
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pubmed_classified
Does circulating Galectin-3 be Associated With Cardiometabolic Disease in the Community?
yes In this large, community-based sample, circulating Gal-3 was associated with abdominal adiposity, dyslipidemia, and hypertension in cross-sectional analyses, but Gal-3 did not predict incident cardiometabolic disease after adjusting for cardiometabolic risk factors. Future investigations should focus on further elu...
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train
medical_symptom_reasoning_easy
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Hello doctor,I was recommended by my cardiologist for a heart valve replacement surgery as my latest echocardiogram results, both transthoracic (TTE) and transesophageal (TEE), revealed that my mitral valve prolapse had worsened. The diagnosis was severe eccentric MR. However, during the latest TTE scan, the radiograph...
Hello. First of all, the severity of MR (mitral regurgitation) will be correctly deciphered by your cardiologist. An eccentric type of MR is actually a grade higher than what it looks. Like your radiologist may think it is moderate but it is severe, but because of its eccentric nature, it looks lesser than what it is. ...
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Hello .. I suffer for ten days from the problem in the left foot began numbness in the instep I went on down to the hospital for fear of a blockage or clots in the leg .. in the hospital worked my blood analysis of a blood clot and analysis of vitamin B12, as well as vitamin D and the results were and Praise are all go...
Welcome to Chat Doctor I have gone through your query and understand your concern. I think you are having problem of sciatica which is probably related to pressing of nerve in back. You can get MRI lumbar spine to get a clue to whether nerves are pressed or not. Analgesic(you are already taking naproxen) are helpful in...
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Does immunosuppression associated with interleukin-1R-associated-kinase-M upregulation predict mortality in Gram-negative sepsis ( melioidosis )?
yes Immunosuppression in sepsis caused by B. pseudomallei is associated with an upregulation of IRAK-M and an indicator of poor outcome.
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train
medical_disease_knowledge_easy
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What information is there about neuropathic pain (diabetic neuropathy), sleep disorders and iron infusions? I have been anemic for at leat 25 years, despite red meat, iron supplements etc. I have been evaluated by hematology with no real answer why, but now my neurologist is recomending an iron infusion.
Hithanx for using ChatDoctordiabetic neuropathy is one of the most troublesome complication of longstanding diabetes with your added problems of anemia sleep disorders you seem to be in stress leading to anxiety neurosis. Long term anemia for 25 years please get evaluated for renal function tests, any uterine problems ...
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Hello doctor,I have been on Fluoxetine antidepressant drug for a few years. I just started to notice few change, but I do not know what to do. I am getting more headaches than normal, restless legs at night and hot sweat most of the day and night. Are my problems related to the drug? Can you prescribe any medicine for ...
Hello, Welcome to Chat Doctor forum. Yes, the problems you are facing are most likely related to long-term side effects of the ChatDoctor. Mild headaches and sweating are known side effects intrinsic to Fluoxetine. Usually this
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medical_clinical_qa_medium
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Hi doctor,I had cataract surgery. I can see objects only with the rigid lens and it is blurry. I cannot read anything. My eyes still get hurt by bright light and my pupils are big. Why?
Hi, Welcome to Chat Doctor forum. After the cataract surgery, pupil may remain dilated due to surgical trauma to constrictor pupillae muscle or iris is damaged and becomes atrophic. Some ChatDoctor. Make sure you are not using any dilating
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Does dietary lipoic acid supplementation prevent fructose-induced hypertension in rats?
yes Dietary alpha-lipoic acid supplementation in fructose-treated WKY rats may prevent their increase in systolic blood pressure by normalizing cytosolic [Ca2+], blood glucose and insulin, kidney and aortic aldehyde conjugates and preventing adverse renal vascular changes.
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Hello Doctor, My baby is now 6 months he had phimosis (balloning and narrow stream of urine). We had taken him to doctor for thrice and thrice he slightly retracted his foreskin until meatus was shown, my baby s foreskin shown little tear for 3 times and he prescribed ofloxacin antibiotic and clobetasol however we did ...
Hi, It seems that due to pinhole opening of foreskin there might be having balloting while passing urine. If there is no pain while passing urine, nothing to worry. Wait till he becomes one year or more and then go for circumcision operation.Meanwhile make a habit of cleaning of Sega from the glans by gently averting f...
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medical_explanation
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medquad_nih
What is (are) Enlarged Prostate (BPH) ?
The prostate is a gland in men. It helps make semen, the fluid that contains sperm. The prostate surrounds the tube that carries urine out of the body. As men age, their prostate grows bigger. If it gets too large, it can cause problems. An enlarged prostate is also called benign prostatic hyperplasia (BPH). Most men w...
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train
medical_medical_explanation_easy
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treatment_overview
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medquad_nih
What are the treatments for spinocerebellar ataxia type 3 ?
These resources address the diagnosis or management of SCA3: - Gene Review: Gene Review: Spinocerebellar Ataxia Type 3 - Genetic Testing Registry: Azorean disease These resources from MedlinePlus offer information about the diagnosis and management of various health conditions: - Diagnostic Tests - Drug Therapy - Surge...
true
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train
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hai i m suffering from anxiety and depression. i m taking lonazep 0.25 in morning n 0.5 in night. and also taking rexipra 10 mg in morning. i m getting motion problem often. sweating often. is these because of the meditions. is there any alternative medition with less side effects.
Hello, Rexipra may cause constipation and decreased urine output. But it may not cause sweating, it may be due to hot climate or cardiac problem or hypothyroidism etc. Until examination is done it is difficult to say what it is. Please consult with your physician he will check for above conditions with ECG and thyroid ...
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Do adipocytokines attenuate the association between visceral adiposity and diabetes in older adults?
yes Adiponectin is associated with lower odds of diabetes in older men and women. Whereas several adipocytokines explained the relationship between visceral adiposity and diabetes in men, only adiponectin partially mediated this association among women.
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medquad_nih
What are the treatments for Empty Sella Syndrome ?
Unless the syndrome results in other medical problems, treatment for endocrine dysfunction associated with pituitary malfunction is symptomatic and supportive. Individuals with primary ESS who have high levels of prolactin may be given bromocriptine. In some cases, particularly when spinal fluid drainage is observed, s...
true
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train
medical_treatment_overview_easy
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icliniq
Hello doctor,My urine is foamy. I am confused whether everyone will get bubble and foamy urine while urinating. Please explain me.
Hi, Welcome to Chat Doctor forum. I appreciate your vigilance. Mild frothing of urine is usual, but excess of frothing denotes protein leakage in urine. What is your age? Do you notice any swelling of your feet and face? Do you have any other medical problem? To be sure get a urine routine microscopy report and follow ...
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Is insulin resistance related to impaired lung function in morbidly obese women : a case-control study?
yes Insulin resistance is related to respiratory function impairment in morbidly obese women. Our results strongly suggest that the metabolic pathways related to insulin resistance are crucial in initiating lung abnormalities previously described in type 2 diabetic patients. Copyright © 2010 John Wiley & Sons, Ltd.
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Hello doctor,A 4-year-old kid of 15 kg weight is having a general cold for almost three months. Sometimes cough, and nasal congestion. Otherwise, he is fine. He has no fever or weakness.
Hello, Welcome to ChatDoctor. I understand your concern for your child. As you told me, this is happening for long. And there is no fever, it seems to be some allergic condition. Are you still bottle feeding the kid? Is there any difficulty in breathing? Any sounds or snoring while breathing or sleeping? Give syrup Max...
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train
medical_clinical_qa_medium
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explanation
medical
medical_explanation
easy
medquad_nih
What is (are) Acute Myeloid Leukemia ?
Leukemia is cancer of the white blood cells. White blood cells help your body fight infection. Your blood cells form in your bone marrow. In leukemia, however, the bone marrow produces abnormal white blood cells. These cells crowd out the healthy blood cells, making it hard for blood to do its work. In acute myeloid le...
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train
medical_medical_explanation_easy
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My son is 5months and 16days old and he was suffering from severe cough which is now reduced as the Doctor has put him on Augmentin Antibiotic and now he is normal, The doctor now has advised for Septillin syrup from Himalaya to be given for one month minimal which will help him increase immunity. Is it safe to give it...
Most of the episodes of cough and cold are caused due to certain viruses. Antibiotics are generally not required, but some doctors give antibiotics with the assumption of super added bacterial infections which are sometimes present. Reptilian is supposed to act as an immunomodulator and help in enhancing immunity, but ...
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train
medical_drug_information_medium
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Hello doctor,I am a 58-year-old female with a history of hysterectomy twenty years before. Now, I have osteoporosis and I do not want to take a medicine after viewing all the side effects. I am having difficulty in losing weight despite many diets. After searching on the web, I decided to do hormone test and now I want...
Hello. Your thyroid profile is absolutely normal. Your other hormones show postmenopausal status which is normal at your age. For osteoporosis, you should take calcium and vitamin D which you are already taking. You should also start with hormone therapy for the shortest duration and lowest dose as it is not harmful Th...
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medical
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medquad_nih
What are the genetic changes related to Lowe syndrome ?
Mutations in the OCRL gene cause Lowe syndrome. The OCRL gene provides instructions for making an enzyme that helps modify fat (lipid) molecules called membrane phospholipids. By controlling the levels of specific membrane phospholipids, the OCRL enzyme helps regulate the transport of certain substances to and from the...
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pubmed_classified
Do electronic reminders improve procedure documentation compliance and professional fee reimbursement?
yes The complexity of the tertiary care process results in documentation deficiencies. Inexpensive automated reminders can drastically improve compliance without the need for complicated negative or positive feedback.
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train
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medquad_nih
What is (are) Anonychia congenita ?
Anonychia congenita is an extremely rare nail disorder characterized by the complete absence (anonychia) or abnormally developed fingernails and toenails. Affected individuals usually do not have hair, teeth, or bone abnormalities. Signs and symptoms are variable, even among affected members of the same family. Less th...
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Does transdermal oxygen improve sternal wound oxygenation in patients recovering from cardiac surgery?
no Additional inspired oxygen improved Pao(2) and sternal wound PsqO(2) after bypass and may, consequently, reduce infection risk. However, oxygen insufflated locally into an occlusive dressing did not improve wound PsqO(2) and, therefore, does not appear to be useful clinically in cardiac surgery patients to reduce st...
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medquad_nih
What are the genetic changes related to carnitine palmitoyltransferase I deficiency ?
Mutations in the CPT1A gene cause CPT I deficiency. This gene provides instructions for making an enzyme called carnitine palmitoyltransferase 1A, which is found in the liver. Carnitine palmitoyltransferase 1A is essential for fatty acid oxidation, which is the multistep process that breaks down (metabolizes) fats and ...
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Is quality of life favorable for most patients with multiple sclerosis : a population-based cohort study?
yes Though MS can cause significant disability, most patients with MS in the Olmsted County prevalence cohort continue to report a good QOL.
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What are the treatments for Darier disease ?
These resources address the diagnosis or management of Darier disease: - Genetic Testing Registry: Keratosis follicularis These resources from MedlinePlus offer information about the diagnosis and management of various health conditions: - Diagnostic Tests - Drug Therapy - Surgery and Rehabilitation - Genetic Counselin...
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Hi doctor,For almost a week, I have throat itching and some blood coming out of it. I had throat infections in the past and was smoking back then. Now, I do not smoke and it has been more than two and half months that I had a smoke. Could this be because of Nicotex 2 mg that I have been chewing to keep the cravings awa...
Hi. For one event of little blood, you need not have to panic. In my opinion, I do not think it is due to Nicotex (Nicotine) and hence you can continue using Nicotex. Most likely you are having throat infection and most of the times it is due to viral infection and it does not require antibiotic such as Azithral (Azith...
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train
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icliniq
Hello doctor,My whole body gets itchy after sex. Earlier it used to be random, but now it is almost every time. My face, neck, chest, legs, even hands, and arms are involved. I am 29 years old.
Hello, Welcome to Chat Doctor forum. According to your statement, you are suffering from allergy just after sex. You did not mention here whether your partner uses condoms or not. You may be allergic to the condoms or any added ingredient like spermicide that you or your partner used. Although it is possible to be alle...
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Is exposure to bisphenol A associated with recurrent miscarriage?
yes Exposure to bisphenol A is associated with recurrent miscarriage.
true
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train
medical_disease_knowledge_easy
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healthcaremagic
I have had an experience a few days ago regarding my heart . I was sitting at my office chair when I suddenly got this heavy ache in my chest the pain was pressure and a hot ache so extreme that I couldnt breath and my jaw started aching as well. I managed to flag a co worker with my hand and I couldnt talk the pain wa...
Hi thanks for contacting Chat Doctor... You have not mentioned test that you have done ..... You are suffering from sudden left side chest pain which when comes remain for sometimes.... Investigate with.....-blood pressure measurement -2D echo -tread meal test If above normal then cardiac cause ruled out. Now for furth...
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healthcaremagic
I am 37 yrs old, never ever had any health issues at all in my life past the occasional headaches etc. I recently had felt bad for about a week and wen to doctor because my eyes wer turning yellowish color as was my skin . later to find out that it was jaundice due to my alt/glucose to high that cause a high bilirubin ...
Hi, I hope you are very well. The study of alterations in hepatic chemistry consists of
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open_ended
en
train
medical_drug_information_hard
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icliniq
Hello doctor,My baby is having a fever. Morning around 8 it was 100. I have given him Crocin. Around 12.30 his temp was 101.3. So I have given him Meftal P. Now (5.30) again the temperature is 100.3. What should I give him now? Crocin or Meftal? What should be the time gap?
Hello. I got your concern. Initially, it looks like a viral fever. Let us wait and watch for the pattern of fever. Yes, for fever, if less than 100 F, do just tap water sponging all over the body. If 100 F to 102 F, give Paracetamol as and when the fever comes with a gap of six hours between two doses. If fever is more...
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open_ended
en
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medical_clinical_qa_medium
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reasoning
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pubmed_classified
Do paleolithic and Mediterranean Diet Pattern Scores Are Inversely Associated with Biomarkers of Inflammation and Oxidative Balance in Adults?
yes These findings suggest that diets that are more Paleolithic- or Mediterranean-like may be associated with lower levels of systemic inflammation and oxidative stress in humans.
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open_ended
en
train
medical_disease_knowledge_easy
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medical_explanation
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medquad_nih
What is (are) Alzheimer's Disease ?
Alzheimer's disease (AD) is an age-related, non-reversible brain disorder that develops over a period of years. Initially, people experience memory loss and confusion, which may be mistaken for the kinds of memory changes that are sometimes associated with normal aging. However, the symptoms of AD gradually lead to beh...
true
open_ended
en
train
medical_medical_explanation_easy
a8f339df-98d3-4592-9a5a-5eb65535087c
explanation
medical
treatment_overview
easy
medquad_nih
What are the treatments for metatropic dysplasia ?
These resources address the diagnosis or management of metatropic dysplasia: - Gene Review: Gene Review: TRPV4-Associated Disorders - Genetic Testing Registry: Metatrophic dysplasia These resources from MedlinePlus offer information about the diagnosis and management of various health conditions: - Diagnostic Tests - D...
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medical_treatment_overview_easy
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pubmed_classified
Do validation of Duruöz Hand Index in patients with tetraplegia?
yes The DHI was found a valid method in the assessment of hand functions in patients with tetraplegia.
true
open_ended
en
train
medical_disease_knowledge_easy
43fe73d6-cf55-473d-bae6-f81981091481
explanation
medical
treatment_overview
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medquad_nih
What are the treatments for fumarase deficiency ?
These resources address the diagnosis or management of fumarase deficiency: - Gene Review: Gene Review: Fumarate Hydratase Deficiency - Genetic Testing Registry: Fumarase deficiency These resources from MedlinePlus offer information about the diagnosis and management of various health conditions: - Diagnostic Tests - D...
true
open_ended
en
train
medical_treatment_overview_easy
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