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48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Aortic Valve Stenosis Had TAVI procedure in UK Nil | 0 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Aortic Valve Stenosis Aortic Valve Insufficiency Transcatheter Aortic Valve Replacement Patients in whom transcatheter aortic valve implantation is attempted at participating center None except failure to obtain informed consent | 0 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Cystic Fibrosis Confirmed diagnosis of CF Forced expiratory volume in 1 second (FEV1) 40-90% predicted Non-smoker and non-tobacco user for a minimum of 30 days prior to screening and for the duration of the study Participation in another clinical trial or treatment with an investiga... | 0 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Dysphagia Dysphonia Postoperative Pain Patients > 18 years of age 2. Primary two and three-level ACDF between C3-7 3. Approved pre-authorization to undergo the procedure Patients < 18 years of age 2. Patients who are unable to give their own consent 3. Revision ACDF 4. Combined ante... | 0 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Aortic Valve Stenosis Heart Valve Diseases Heart Diseases Cardiovascular Diseases Ventricular Outflow Obstruction Patient with severe degenerative native aortic stenosis (AS) Patient at high risk for open surgical valve replacement Patient symptomatic according to NYHA functional cla... | 1 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 0.0-999.0, Aortic Valve Stenosis Severe aortic stenosis, defined as aortic valve area of <1.0 cm2 (or aortic valve area index of <0.6 cm2/m2) by the continuity equation, AND mean gradient >40 mmHg OR maximal aortic valve velocity >4.0 m/sec by resting echocardiogram 2. Society of Thoracic Surgeo... | 1 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Valve Heart Diseases All consecutive patients referred for organic MR and/or AR at least moderate to severe according to the ESC guidelines criteria⁴ will be eligible. The moderate to severe will defined by echocardiography as followed MR: an effective regurgitant orifice area (EOA) ... | 1 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 50.0-85.0, Heart Valve Diseases Coronary Artery Disease Patient indicated for first-time non-emergent procedure under cardiopulmonary bypass which is expected to last up to 6 hours. 2. Patient undergoing an elective isolated coronary artery bypass surgery (CABG), or an elective isolated aortic/m... | 1 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Acute Kidney Injury Renal Insufficiency, Chronic Heart Failure Myocardial Infarction Arrhythmias, Cardiac Stroke Subjects are eligible to participate if they are undergoing TAVR for aortic stenosis at the University of Texas Southwestern Medical Center The patient cannot or will not... | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Severe and Symptomatic Aortic Stenosis Stable Coronary Disease Patients older than 18 years Severe and symptomatic aortic stenosis defined as a median trans-valvular gradient higher than 40 mmHg and an aortic valve area of less than 1.0 cm2 or 0,6 cm2/m2 on echocardiography associate... | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 70.0-999.0, Aortic Valve Stenosis 70 years of age or older 2. Echocardiographic or hemodynamic based evidence of calcific (senile) aortic stenosis with one of the following: aortic valve EOA <1.0 cm2 or 0.6 cm2/m2 , mean aortic valve gradient >40 mmHg or peak aortic valve velocity >4 m/sec 3. Sy... | 1 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Aortic Valve Disease Age 18 or greater Patients with known BAV diagnosed by echocardiography, previous MRI, or cardiac CT Scheduled for cardiac MRI or have had a cardiac MRI within the past year Able to provide informed consent Ambulatory and expected to be able to complete 6 minute ... | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 22.0-999.0, Mitral Annular Calcification Subject has severe native mitral annular calcification associated with mitral stenosis and/or regurgitation. Qualifying echo must be within 60 days of the date of the procedure Subject has a clinical indication for mitral valve replacement, as demonstrate... | 1 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Aortic Stenosis Group 1 : non aortic stenosis Goup 2, 3 and 4 : aortic stenosis | 1 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Acute Kidney Injury Provide written informed consent 2. Age ≥ 18 years of age 3. Elective cardiac or aortic surgery with CPB>90 minutes 4. Stable pre-operative renal function without evidence of plasma creatinine level increase of ≥ 0.3 mg/dL over the prior 3 months and without renal... | 1 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 70.0-999.0, Aortic Valve Stenosis 70 years of age or older 2. Echocardiographic or hemodynamic based evidence of calcific (senile) aortic stenosis with one of the following: aortic valve EOA <1.0 cm2 or 0.6 cm2/m2 , mean aortic valve gradient >40 mmHg or peak aortic valve velocity >4 m/sec 3. Sy... | 1 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Cardiomyopathy, Hypertrophic Cardiomyopathy, Hypertrophic, Familial Key Hypertrophic cardiomyopathy with symptoms of moderate-to-severe heart failure Left ventricular hypertrophy with maximum LV wall thickness ≥ 15 mm Left ventricular ejection fraction ≥ 50% Able to perform exercise ... | 0 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 1.0-31.0, B Acute Lymphoblastic Leukemia Central Nervous System Leukemia Ph-Like Acute Lymphoblastic Leukemia Testicular Leukemia Patients must be enrolled on APEC14B1 and consented to Screening on the Part A consent form prior to enrollment on AALL1131 White Blood Cell Count (WBC) Age 1-9.99 ye... | 0 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Congestive Heart Failure Heart Failure, Left-Sided Left-Sided Heart Failure Heart Failure with Preserved Ejection Fraction (HFpEF) Normal left ventricular ejection fraction (≥50%) Elevated Left Ventricular filling pressures at cardiac catheterization (defined as resting Pulmonary Cap... | 1 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Bicuspid Aortic Valve bicuspid aortic valve, confirmed by transthoracic or transesophageal echocardiography With or without an aneurysm of the ascending thoracic aorta nonsyndromic aortic syndromic pathology antecedent of acute articular rhumatism | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Aortic Valve Disorder Chronic asymptomatic aortic regurgitation grade 3 (moderate to severe) and grade 4 (severe) 2. No indication for the surgical treatment at the time of enrolment 3. LV EF ≥ 50 % 4. Absence of more than mild concomitant valve disease or complex congenital heart di... | 1 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Aortic Valve Stenosis Bicuspid Aortic Valve known bicuspid aortic valve calcified mild to moderate aortic valve stenosis on prior echocardiography informed consent provided absence of calcified aortic valve stenosis on echocardiography presence of severe aortic valve stenosis histor... | 1 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Pain Hernia MUST HAVE TO Inclusion/ Active Duty members and DoD beneficiary patient 18 years or older Elective, open unilateral inguinal herniorrhaphy using Lichtenstein (tension free with mesh) hernia repair technique Agree to take only the prescribed oral analgesic medication (oxy... | 0 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Heart Disease Age > 18 Patient who underwent a transcatheter aortic valve implantation Patient who provided informed, written consent to participate to TAVI study Patient for whom a CT-Scan performed before TAVI procedure is available none | 0 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Ischemic Heart Disease Stable ischemic heart disease and previous percutaneous coronary intervention (PCI Under optimal medical treatment including aspirin and cholesterol lowering drugs (statins) PCI treatment during the last 30 days Inability to provide informed consent Already fo... | 0 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Aortic Stenosis Subject must be at least 18 years old 2. Severe aortic stenosis defined as Mean aortic gradient > 40 mmHg or Peak jet velocity > 4.0 m/s or Aortic valve area of < 0.8 cm2 3. High risk patient determined by a multidisciplinary heart team consensus (cardiologist and car... | 1 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Severe Symptomatic Aortic Stenosis Stable patients with severe symptomatic aortic stenosis Patient undergoing planned TF-TAVI with the prosthesis TF-TAVI using a minimalist approach of local anesthesia and conscious sedation The use of other (than Edwards or XT) transcatheter aortic... | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-100.0, Valvular Heart Disease Stenosis and Regurgitation (Diagnosis) Presence of aortic stenosis, mitral or aortic regurgitation at the time of an echocardiography at the "Cliniques Universitaires Saint Luc" | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-80.0, Heterozygous Familial Hypercholesterolemia Men or women with heterozygous FH aged between 18 and 80 years FH patient carrying a documented mutation in the LDL receptor gene Subjects must be willing to give written informed consent and able to adhere to visit schedule Men or women < 1... | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 0.0-999.0, Severe Aortic Stenosis At least one cardiologist and one cardiac surgeon agree that it is difficult for the patient to receive a surgical procedure due to medical factors such that the subject has various comorbidities and he/she is more likely to die or suffer from severe diseases th... | 1 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Aortic Valve Disease Signed Informed Consent 2. Age ≥18years of age 3. Presents with symptomatic aortic stenosis and/or aortic regurgitation, as well as NYHA rating of NYHA ≥ II 4. Has undergone the diagnosis of at least one interventional cardiologist and two cardiac surgeons: the p... | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Atrial Fibrillation Age 18+ on index date Patients must have been prescribed either dabigatran, rivaroxaban, or apixaban identified by pharmacy claim during the study period. The first dispensing date of either study drug will be defined as the index date Patients must be treatment n... | 0 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 21.0-999.0, Aortic Valve Stenosis Severe AS who underwent TAVR ascending aorta more than 50mm | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 19.0-999.0, Aortic Valve Stenosis The patient agrees to participate in this study by signing the informed consent form. Alternatively, a legally authorized patient representative may agree to the patient's participation in this study and sign the informed consent form. 2. The patient has a worki... | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Aortic Valve Stenosis Subject has provided written informed consent prior to uploading CT scan to core lab. 2. Subject is ≥ 18 years of age or legal age in host country. 3. Subject's aortic annulus diameter meets the range indicated in the Instructions for Use as measured by multisli... | 1 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-80.0, Heart Failure，Congestive Advanced Heart Failure- Individuals with severely reduced left ventricular systolic function that are scheduled to undergo LVAD insertion uncontrolled diabetes with peripheral neuropathy (interferes with acquisition of MSNA signal) Individuals with clinical r... | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 14.0-999.0, Renal Artery Obstruction Hypertension, Renovascular Age ≥ 14 at the time of informed consent 2. Diameter reduction of renal artery or main branch of renal artery≥ 60%,and ≥2 of four following conditions met:1)systolic hyperemic pressure gradient >20 mm Hg,2)captopril renoscitigraphy ... | 0 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 70.0-999.0, Stenoses, Aortic Valve Age ≥ 70 years Subject has documented calcific, severe native aortic stenosis with an initial AVA of <1.0 cm2 (or AVA index of <0.6 cm2/m2), and a mean pressure gradient ≥40 mm Hg or jet velocity ≥4.0 m/s or doppler velocity index ≤0.25, as measured by echocard... | 1 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Aortic Valve Stenosis severe symptomatic aortic stenosis requiring balloon aortic valvuloplasty cardiogenic shock bilateral absence of radial pulse | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Atrial Fibrillation Aortic Stenosis Severe aortic valve stenosis with an indication for aortic valve replacement (e.g., symptomatic patient, decreased left ventricular (LV) function) Suitable anatomy for transfemoral TAVI with the Portico Transcatheter Aortic Valve System (ileofemora... | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Aortic Valve Stenosis Hypertrophy, Left Ventricular Severe aortic stenosis (aortic valve jet velocity ≥4.0 m/s, or aortic valve area indexed to body surface area <0.6cm2/m2 with aortic jet velocity ≥3.5m/s) 2. Age over 18 years 3. No symptoms attributable to aortic stenosis that requ... | 1 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 0.0-999.0, Aortic Valve Stenosis Subject must be ambulatory (with or without an assist device) Subject has severe aortic stenosis and is felt an appropriate candidate for TAVR by the Heart Team Subject requires 6.0 seconds or longer to complete a 15ft walk test Subject must be able to move betwe... | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Endothelial Dysfunction Aortic Valve Disease Patient ≥ 18 years Patient operated on aortic valvular replacement by bioprosthesis in surgery + CEC or TAVI Signed consent Affiliation to Social Security Any other cardiac surgery Mechanical aortic valve replacement Permanent Ac / Fa Pre... | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 19.0-85.0, Cardiopulmonary Bypass Cardiac Surgery patients who underwent aortic repair or replacement under moderate hypothermic CPB Preoperative: < 19 years old, > 85 years old, emergency operation, reoperation, left ventricular ejection fraction < 50%, arrhythmia, ischaemic myocardial disease... | 0 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 20.0-70.0, Essential Hypertension Dyslipidemia Voluntarily provided a written consent to participate in this clinical study 2. Male or female adults aged 19-70 years 3. Patients must have been confirmed essential hypertension and dyslipidemia at Screening visit (V1) 4. Uncontrolled blood pressur... | 0 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Aortic Valve Disease Severe, calcific bicuspid aortic stenosis. 2. Heart team agrees the patient has a risk of operative mortality and has an STS <8 and >3. 3. The study patient has been informed of the nature of the study, agrees to its provisions and has provided written informed c... | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 19.0-89.0, Heart Failure Age >18 and <90. 2. Established HF with reduced ejection fraction (EF ≤35 %), assessment done within 12 months of index visit. 3. Admitted under observation unit for management of AHF. 4. Heart rate ≥70 beats per minute, with sinus rhythm. 5. Receiving guideline based me... | 1 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Aortic Rupture Age ≥ 18 years Supra-coronary aortic diameter measured by CT-scan or transthoracic/trans-esophageal echocardiography between 40 and 45 mm in case of presence of aortic valve disease, bicuspid aortic valve or connective tissue disease and between 40 and 50 mm in case of... | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Right Ventricular Dysfunction cardiac surgery patients elective, isolated aortic valve replacement or coronary artery bypass grafting in combination with aortic valve replacement age < 18 | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-65.0, Hypertension,Essential Obstructive Sleep Apnea Left Ventricular Hypertrophy confirmation of resistant hypertension(RAH). RAH was recognized when in spite of the use of at least 3 antihypertensive agents (including a diuretic) in maximum doses, it was impossible to achieve the target v... | 1 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-90.0, Coronary Artery Disease Aortic Valve Disease Mitral Valve Disease Coronary artery bypass graft, and mitral/aortic valve replacement patients recovering from sternotomy procedure eligible for cardiac rehabilitation Able to provide written informed consent Male or female 18 years of age... | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 0.0-999.0, Optical Coherence Tomography (OCT) Percutaneous Coronary Intervention (PCI) Single-Photon Emission Computed Tomography (SPECT) Coronary Angiography (CAG) Borderline Coronary Artery Lesions The for this study will be only those participants in whom diagnostic coronary angiography revea... | 0 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Heart Failure With Normal Ejection Fraction Main/reproducibility group: 1. Ability to provide informed consent 2. Typical HF symptoms (NYHA stage II-III) within the last 6 months 3. EF > 45 % with absence of structural heart disease on echocardiography (except left ventricular hypert... | 0 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Obesity Recent VA primary care measured BMI between 30.0-44.9 kg/m2 (at facility in pacific or mountain time zone) Access to DVD player or internet Able to participate fully in all study protocol/procedures including informed consent Inability to speak, read, or understand English R... | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Coronary Artery Disease Coronary Arteriosclerosis Atrial Fibrillation Left Atrial Abnormality Severe Aortic Stenosis symptomatic severe aortic stenosis patients (defined as aortic valve area of < 1 cm2 or 0.6 cm2/m2 by transthoracic echocardiography) referred to aortic valve replacem... | 1 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 20.0-99.0, Troponin Scheduled for transcatheter aortic valve replacement due to aortic stenosis Transapical approach Pre-procedural PaO2 < 65 mmHg or oxygen support therapy Pre-procedural severe kidney injury (end-stage renal disease) Pre-procedural chronic pulmonary disease, symptomatic asthma... | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 0.0-999.0, Severe Aortic Stenosis Transcatheter Aortic Valve Implantation Severe aortic stenosis (Peak transvalvular gradient of ≥ 40mmHg on TTE or stress Echo, Aortic valve area of < 1.0cm2) Symptoms suggestive of aortic stenosis (dyspnea, syncope, angina) Eligible for TAVI (Upon evaluation by ... | 1 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Aortic Valve Stenosis Clinical Trial Depression Frail Elderly Syndrome Inflammation Symptomatic aortic valve stenosis Planned elective transcatheter aortic valve replacement Willingness and ability to provide signed informed consent (IC) form prior to participation in any study-relat... | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 55.0-999.0, Aortic Stenosis Arteriosclerosis Familial Hypercholesterolemia Conventional Transthoracic Echocardiogram Cases Age ≥ 65 years at the time of cardiac ultrasound Genetically diagnosed HFH or in a first-degree relative History of hypercholesterolemia with LDLc levels> 220 mg / dL withou... | 1 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Deep Vein Thrombosis Abdominal Aortic Aneurism Pneumothorax Gallbladder Diseases Hydronephrosis Pregnancy, Ectopic Ascites Pleural Effusion Pericardial Effusion Emergency department patient A suspected medical condition, that can be confirmed or excluded by basic POCUS exam, includin... | 0 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Aortic Stenosis Myocardial Fibrosis Left Ventricular Hypertrophy (aortic stenosis group) Age over 18 Severe aortic stenosis with planned aortic valve replacement (control group) Age over 18 Planned non-aortic valve cardiac or elective ascending aorta surgery (aortic stenosis group) ... | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-85.0, Carotid Artery Plaque Atherosclerosis Ischemic Stroke bearing an asymptomatic carotid stenosis of 30-70% in diameter, as established by Doppler-measured peak systolic flow velocity, according to the Society of Radiologists in Ultrasound Consensus Conference (Grant et al. Radiology 200... | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Hip Disease Males or females over the age of 18 have undergone a THA surgery during the period of interest January 2013 to July 2016) excluded from the study based on the following 1. Concurrent, painful, physical condition or concurrent surgery that may require analgesic treatment ... | 0 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 70.0-999.0, Aortic Stenosis Transthyretin Amyloidosis (AS group) Severe aortic stenosis Referred for aortic valve intervention (surgical AVR / TAVI) High clinical suspicion of amyloid (e.g. low-flow low-gradient AS, inappropriate LVH) Age >70 years Willing and able to comply with study protocol ... | 1 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-90.0, Coronary Artery Disease Aortic Valve Stenosis Age > 18 years 2. Written informed consent 3. Diagnosis of severe native aortic valve disease with the indication to endovascular valve replacement given by Heart Team 4. Diagnosis of at least one coronary stenosis >50% at angiography 5. N... | 1 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Carotid Arteries Patients presenting a. to the neurologist for evaluation of stroke or TIA (Symptomatic) with: i. Symptomatic patients with plaque ≥70% in at least one carotid artery that would be implicated as the source of embolus responsible for the stroke/TIA. b. or to the vascul... | 1 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Aortic Valve Stenosis Patients who underwent transcatheter (TAVI) or surgical aortic valve replacement (SAVR) for severe aortic valve stenosis Patients aged >18 years Primary aortic valve procedure with a bioprosthesis for AS with or without associated regurgitation TAVI and SAVR wit... | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 21.0-80.0, Aphasia Stroke Stroke, Ischemic Aphasia, Broca Aphasia, Global Aphasia, Mixed Aphasia, Jargon Aphasia, Expressive Aphasia, Conduction Aphasia, Fluent Aphasia, Anomic Experienced a left hemisphere ischemic or hemorrhagic stroke At least 12 months post-stroke Primarily English speaker f... | 0 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 0.0-999.0, Aortopathies Thoracic Aortic Aneurysm Aortic Valve Disease Thoracic Aortic Disease Thoracic Aortic Dissection Thoracic Aortic Rupture Ascending Aortic Disease Descending Aortic Disease Ascending Aortic Aneurysm Descending Aortic Aneurysm Marfan Syndrome Loeys-Dietz Syndrome Ehlers-Dan... | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 20.0-110.0, Coronary Artery Stenoses Aortic Stenosis All patients who have coronary stenoses between 40-70% severity and who have severe aortic stenosis undergoing TAVR work-up Patients with documented intraprocedural hemodynamic instability, shock, or major adverse event (myocardial infarction... | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 0.0-999.0, Aortic Stenosis Symptomatic patients with severe aortic stenosis Institution heart team determines that aortic valve replacement neoTM device using its transapical delivery system is appropriate Patients unable or unwilling to give inform consent | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Aortic Valve Stenosis Mitral Regurgitation Heart Murmurs Valvular Heart Disease Able to provide consent Undergoing a complete echocardiogram Refusal to participate | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 19.0-999.0, Aortic Stenosis Symptomatic Aortic Stenosis Aortic Regurgitation Subjects who are considered to be operable and high risk for surgical valve replacement: STS Score ≥ 8 and ≤ 15 or Logistic EuroSCORE ≥ 15 and ≤ 40. If STS score is below 8 and Logistic EuroSCORE is below 15, patients s... | 1 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 30.0-90.0, Coronary Artery Disease Aortic Valve Stenosis Mitral Valve Insufficiency An eligible patient with coronary artery disease, aortic valve stenosis or mitral valve insufficiency scheduled for elective coronary artery bypass grafting, aortic valve replacement or mitral valve repair operat... | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 0.0-999.0, Aortic Valve Stenosis Severe, calcific aortic stenosis meeting the following transthoracic echocardiogram Aortic valve area ≤ 1.0 cm2 OR aortic valve area index ≤ 0.6 cm2/m2 Jet velocity ≥ 4.0 m/s OR mean gradient ≥ 40 mmHg 2. New York Heart Association functional class ≥ II 3. Judged... | 1 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Bicuspid Aortic Valve Adults over 18 years of age confirmed BAV by TTE computed tomography or MRI Adults benefiting from a social security scheme having received information on the research having signed the consent form Patient with a syndromic form of BAV Loeys-Dietz syndrome Turn... | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Bicuspid Aortic Valve Age ≥18 years. 2. NYHA≥2 and/or syncope and/or angina. 3. Patient judged by the Heart Team as indicated for TAVI. 4. Anatomical suitability for transfemoral-TAVI with Evolut Pro or Evolut R XL, based on MSCT assessment. 5. Estimated life-expectancy>1 year Age <... | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 0.0-999.0, Fontan Procedure This study will includeall patients referred for an elective TCPC procedure at the period of the study, who demonstrated a standard risk profile Preoperative evaluation consisted of ECG, transthoracic echocardiogram, and complete cardiac catheterization. Patients with... | 0 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 0.0-999.0, Right Bundle-Branch Block Heart Failure With Reduced Ejection Fraction Bifocal Stimulation Patients with RBBB and HFrEF (defined by left ventricular ejection fraction ≤35%) in sinus rhythm, who remain in NYHA class II-III or ambulatory NYHA class IV despite OMT Refusal or withdrawal ... | 1 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 0.0-999.0, Right Ventricular Dysfunction Rheumatic Heart Disease All ages will be accepted Isolated mitral valve lesion either stenosis or regurge Good LV function (EF <45%) Any degree of tricuspid valve regurge Concomitant Aortic valve lesion needs replacement Poor LV function (Low EF> 45%) Ot... | 1 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-85.0, Heart Failure With Normal Ejection Fraction Left Ventricular Hypertrophy Aortic Valve Stenosis Diabetes Group 1: Healthy Volunteers (n = 30) Healthy adults with no known history of medical disease Age 18-85 years No history cardiovascular disease Ability to provide informed consent Gr... | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 0.0-999.0, Aortic Valve Stenosis Arrythmia Patients with severe aortic stenosis accepted for a TAVI procedure by the Heart Team Urgent TAVI procedure or logistic reasons precluding an ECG monitoring of at least 1 week within the 3 months prior to the TAVI procedure Prior permanent pacemaker | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Aortic Valve Stenosis elective patients with a diagnosis of severe symptomatic aortic stenosis and admitted for TAVI patients not providing written informed consent | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 20.0-999.0, Aortic Valve Aortic Valve Insufficiency Aortic Regurgitation Regurgitation, Aortic Valve Aortic Incompetence Patients must have co-morbidities such that the principal investigator and co-investigator concur that the predicted risk of operative mortality is ≥15% (STS score ≥10 OR Logi... | 1 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 0.0-18.0, Hypertension, Pulmonary -patients of any age with congenital cardiac disease coming for catheterization of the right heart, or both the right and left heart active systemic infection current active cancer active cancer treatment prior bone marrow transplant prior solid organ transplan... | 0 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Chest Pain Coronary Artery Disease Acute Coronary Syndrome Ischemic Heart Disease Patients above 18 years of age with ischaemic sounding chest pain prompting visit to the emergency department (suspected ACS). 2. No-ischaemic ECG changes (i.e. no ST-segment elevation or depression 1mm... | 0 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Aortic Stenosis, Calcific Severe aortic stenosis (aortic valve area <1.0cm2 or aortic valve area index <0.6 cm2/m2 Age ≥18 years Signed informed patient consent form Severe valvular disease other than AS Significant coronary heart disease requiring revascularisation History of myoca... | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 0.0-999.0, Aortic Valve Stenosis patients undergoing transfemoral transcatheter aortic valve procedures valve-in-valve procedures, other acces routes than transfemoral | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Aortic Insufficiency Aortic Stenosis Mitral Insufficiency Mitral Insufficiency and Aortic Stenosis Tricuspid Regurgitation Insufficiency, Pulmonary Insufficiency, Tricuspid Adults with a heart defect verified by echocardiography | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 17.0-75.0, Aortic Valve Replacement 75 years old patients with sever aortic valve stenosis undergoing valve replacement surgery informed consent has been obtained Planned off-pump cardiac surgery Patients required intra-aortic balloon pump under 17 years of age | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Functional Mitral Regurgitation Adults ≥18 years of age 2. Symptomatic FMR of grade moderately severe to severe (3 to 4) due to either ischemic or non-ischemic dilated cardiomyopathy with structurally normal leaflets determined by echocardiography (preferably with echocardiographic e... | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Aortic Valve Stenosis Subject has documented severe aortic stenosis defined as initial AVA ≤1.0 cm2 (or AVA index ≤0.6 cm2/m2) AND a mean pressure gradient ≥40 mm Hg OR maximal aortic valve velocity ≥4.0 m/s OR Doppler velocity index ≤0.25 as measured by echocardiography and/or invas... | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Morality Retrospectively, all patients examined from January 1, 2000 to November 2014 will be included in the echocardiography laboratory whose objective examination is a narrowing of the aortic valve (maximum transaortic velocity ≥2.5 m / s) Aortic stenosis may be known in the past ... | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 0.0-999.0, Aortic Valve Stenosis Patients with severe symptomatic aortic stenosis undergoing TAVI Patients with concomitant valvular heart disease | 1 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 60.0-999.0, Bicuspid Aortic Valve Severe aortic stenosis, defined as follows: 1. For symptomatic patients: Aortic valve area ≤1.0 cm2 (or aortic valve area index of ≤0.6 cm2/m2), OR mean gradient ≥40 mmHg, OR Maximal aortic valve velocity ≥4.0 m/sec by transthoracic echocardiography at rest 2. F... | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-999.0, Assessment of the RV Function in Patients With Heart Faliure - Adult patients of both gender who have the followiong : (i) symptoms with or without signs of HF (ii) elevated natriuretic peptides (BNP ≥35pg/ mL or NT-proBNP≥125pg/mL) (iii) relevant structural heart disease: left ventr... | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 19.0-80.0, Aortic Stenosis Aortic Regurgitation Hypertension LVM Left Ventricular Hypertrophy Male or female aged ≥ 19 years and < 80 years 2. Diagnosis of mild-moderate AS or mild-moderate AR 3. Applicable to 2.0~3.9 m/s of aortic jet velocity for mild-moderate AS or to 0.2~0.6 cm of Vena contr... | 1 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-49.0, Cystic Fibrosis (HV Subjects): 1. Written informed consent given by the subject. 2. At least ≥ 18 years old and < 50 years of age. 3. Healthy with no acute medical condition for ≥ 2 weeks prior to screening and no known chronic medical condition requiring regular medical follow up and... | 0 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 0.0-999.0, Valvular Heart Disease (Aortic and Mitral Valves) Patients with clinically diagnosed valvular heart disease and confirmed by echocardiography Patients with known contraindication to MRI including the presence of paramagnetic Surgical clips, or pacemakers Severely ill patients Claustr... | 2 |
48 M with a h/o HTN hyperlipidemia, bicuspid aortic valve, and tobacco abuse who presented to his cardiologist on [**2148-10-1**] with progressive SOB and LE edema. TTE revealed severe aortic stenosis with worsening LV function. EF was 25%. RV pressure was 41 and had biatrial enlargement. Noted to have 2+ aortic insuff... | eligible ages (years): 18.0-75.0, Acute Decompensated Heart Failure Patients are eligible for enrollment if within the previous 24 hours they were treated with acute decompensated heart failure or diagnosed on the basis of the investigator's clinical diagnosis of heart failure, which needs to be supported by at least ... | 1 |
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